Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
adsorption / desorption: screening
Data waiving:
study technically not feasible
Justification for data waiving:
the study does not need to be conducted because the substance has a low octanol water partition coefficient and the adsorption potential of this substance is related to this parameter
Cross-referenceopen allclose all
Reason / purpose for cross-reference:
data waiving: supporting information
Reference
Endpoint:
partition coefficient
Type of information:
(Q)SAR
Adequacy of study:
key study
Reliability:
3 (not reliable)
Rationale for reliability incl. deficiencies:
results derived from a valid (Q)SAR model and falling into its applicability domain, with limited documentation / justification
Justification for type of information:
Substance is insoluble in water, and is to have an expected partition coefficient above 8, and thus suggested OECD methods are not applicable.
Qualifier:
no guideline followed
Principles of method if other than guideline:
Calculated, KOWWIN programme v1.68; Estimation Programs Interface Suite™ for Microsoft® Windows, v 4.00. United States Environmental Protection Agency, Washington, DC, USA.
GLP compliance:
no
Key result
Type:
log Pow
Partition coefficient:
ca. 19.31
Temp.:
20 °C
pH:
ca. 7
Conclusions:
Estimated Log Kow = 19.31
Reason / purpose for cross-reference:
data waiving: supporting information
Reference
Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to guideline
Guideline:
OECD Guideline 105 (Water Solubility)
GLP compliance:
not specified
Type of method:
column elution method
Key result
Water solubility:
< 0.1 mg/L
Conc. based on:
test mat. (dissolved fraction)
Temp.:
20 °C
pH:
>= 6.4 - <= 6.5
Conclusions:
Preliminary test, in accordance with OECD Method 105 (visual assessment), showed that the water solubility of the test substance is below the detection limit of the analytical method (0.1mg/L). Consequently, the substance appears to be insoluble in water. In reference to Annex VII of REACH, if the substance appears to be insoluble in water, then the “limit test up to the detection limit of the analytical method shall be performed”. Based upon this information, the water solubility of the test substance shall be reported at <0.1mg/L. The water solubility was determined at 20°C. The pH value of the collected aqueous fraction was a range of 6.4-6.5.
Reason / purpose for cross-reference:
data waiving: supporting information
Reference
Endpoint:
partition coefficient
Data waiving:
study technically not feasible
Justification for data waiving:
the study does not need to be conducted because the substance does not dissolve in water or in octanol
Justification for type of information:
The substance is not soluble in water (< 1 mg/L).

Data source

Materials and methods

Results and discussion

Applicant's summary and conclusion