Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Acute Toxicity: other routes

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Administrative data

Endpoint:
acute toxicity: other routes
Type of information:
experimental study
Adequacy of study:
supporting study
Reliability:
2 (reliable with restrictions)

Data source

Reference
Reference Type:
publication
Title:
Comparative toxicity of tetra ethyl lead and tetra methyl lead
Author:
Magistretti, M., Zurlo, N., Scollo, F., Pacillo, D.
Year:
1963
Bibliographic source:
Med. Lavoro 54, pp 486-495

Materials and methods

Principles of method if other than guideline:
other: procedure as detailed in paper by Magistretti et al. (see Reference)
GLP compliance:
not specified

Test material

Constituent 1
Chemical structure
Reference substance name:
Tetraethyllead
EC Number:
201-075-4
EC Name:
Tetraethyllead
Cas Number:
78-00-2
Molecular formula:
C8H20Pb
IUPAC Name:
tetraethylplumbane

Test animals

Species:
rabbit
Strain:
not specified
Sex:
not specified

Administration / exposure

Route of administration:
intravenous
Vehicle:
not specified

Results and discussion

Effect levels
Sex:
not specified
Dose descriptor:
LD50
Effect level:
ca. 14.4 mg/kg bw

Applicant's summary and conclusion