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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Acute Toxicity: dermal

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Administrative data

Endpoint:
acute toxicity: dermal
Type of information:
experimental study
Adequacy of study:
weight of evidence
Reliability:
2 (reliable with restrictions)

Data source

Reference
Reference Type:
publication
Title:
Tetraalkyl lead poisoning
Author:
Akatsuka K
Year:
1973
Bibliographic source:
Japanese Journal of Industrial Health, vol. 15, pp 3-66

Materials and methods

Principles of method if other than guideline:
Method: other (not published)
GLP compliance:
not specified

Test material

Constituent 1
Chemical structure
Reference substance name:
Tetraethyllead
EC Number:
201-075-4
EC Name:
Tetraethyllead
Cas Number:
78-00-2
Molecular formula:
C8H20Pb
IUPAC Name:
tetraethylplumbane

Test animals

Species:
dog
Strain:
not specified
Sex:
not specified

Administration / exposure

Type of coverage:
not specified
Vehicle:
not specified

Results and discussion

Effect levels
Sex:
not specified
Dose descriptor:
LDLo
Effect level:
ca. 547 mg/kg bw

Applicant's summary and conclusion

Interpretation of results:
Category 1 based on GHS criteria