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Environmental fate & pathways

Bioaccumulation: aquatic / sediment

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Administrative data

Endpoint:
bioaccumulation in aquatic species: fish
Type of information:
experimental study
Adequacy of study:
disregarded due to major methodological deficiencies
Study period:
November 18th 1981 - February 19th 1982
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
documentation insufficient for assessment

Data source

Reference
Reference Type:
publication
Title:
Report on the result of measuring concentration degree
Year:
1982
Bibliographic source:
J-Check

Materials and methods

GLP compliance:
not specified

Test material

Reference
Name:
Unnamed
Test material form:
solid: crystalline
Remarks:
white needle crystal

Test solutions

Vehicle:
yes
Details on preparation of test solutions, spiked fish food or sediment:
Preliminary study TLm:
1g of sample and 10g of Tween-80 were dissolved into acetone. Then acetone was evaporated. The mixture was then put in flask and water was added up to 1l. Thus 1000 ppm dispersion solution was obtained.

Test solution:
water= 2 ml/min:800 ml/min
Test solution was made by diluting solution prepared for preliminary study TLm.
#1 area test solution: 80 ppm
#2 area test solution: 8 ppm

Test organisms

Test organisms (species):
Cyprinus carpio
Details on test organisms:
Average weight: 23.4 g
Average length: 9.7 cm
Average lipid content: 4.9% (E.G. Blight and W.J.Dyer, Can. J. Biochem. Physiol., 37, 911 (1959))

Study design

Route of exposure:
aqueous
Test type:
flow-through
Total exposure / uptake duration:
6 wk

Test conditions

Test temperature:
25±1°C
Details on test conditions:
Test bath made of glass.
Volume: 100 l
Quantity of water flowing in: 1155 l/day
Nominal and measured concentrations:
Nominal concentrations: 0.2 ppm w/v, 0.002 ppm w/v in the test bath.
Reference substance (positive control):
not specified

Results and discussion

Lipid content
Lipid content:
4.9 %
Remarks on result:
other: E.G. Blight and W.J.Dyer, Can. J. Biochem. Physiol., 37, 911 (1959)
Bioaccumulation factoropen allclose all
Conc. / dose:
ca. 0.2 other: ppm
Type:
BCF
Value:
>= 6.5 - <= 10 L/kg
Conc. / dose:
ca. 0.02 other: ppm
Type:
BCF
Value:
>= 2.7 - <= 8.1 L/kg

Applicant's summary and conclusion

Validity criteria fulfilled:
not specified
Conclusions:
Under the test conditions, at the nominal concentration dose of 0.2 ppm w/v a BCF >= 6.5 - <= 10.0 L/kg was obtained. At the nominal concentration dose of 0.02 ppm w/v a BCF >= 2.7 - <= 8.1 L/kg was obtained.