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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Toxicity to microorganisms

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Administrative data

Link to relevant study record(s)

Reference
Endpoint:
activated sludge respiration inhibition testing
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2021
Reliability:
1 (reliable without restriction)
Qualifier:
according to guideline
Guideline:
OECD Guideline 209 (Activated Sludge, Respiration Inhibition Test (Carbon and Ammonium Oxidation))
GLP compliance:
yes
Vehicle:
no
Test organisms (species):
activated sludge
Details on inoculum:
Activated sludge was used as inoculum. It was taken from a domestic sewage treatment plant and washed before usage.
Test type:
static
Water media type:
freshwater
Limit test:
no
Total exposure duration:
3 h
Test temperature:
19.2 – 24.0°C
pH:
7.1-7.6
Dissolved oxygen:
The oxygen uptake rate of the blank controls was above 20 mg O2 per gram activated sludge in one hour.
Reference substance (positive control):
yes
Remarks:
3,5-Dichlorophenol was used as positive control. 1 replicate/concentration (all experiments).
Key result
Duration:
3 h
Dose descriptor:
NOEC
Effect conc.:
ca. 320 mg/L
95% CI:
ca. 9.5 - < 14
Nominal / measured:
nominal
Conc. based on:
test mat.
Key result
Duration:
3 h
Dose descriptor:
EC10
Effect conc.:
ca. 92 mg/L
95% CI:
> 39 - < 160
Nominal / measured:
nominal
Conc. based on:
test mat.
Key result
Duration:
3 h
Dose descriptor:
EC50
Effect conc.:
ca. 1 100 mg/L
95% CI:
> 630 - < 2 500
Nominal / measured:
nominal
Conc. based on:
test mat.
Validity criteria fulfilled:
yes

Description of key information

Key value for chemical safety assessment

EC50 for microorganisms:
1 100 mg/L
EC10 or NOEC for microorganisms:
320 mg/L

Additional information