Registration Dossier
Registration Dossier
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EC number: 604-669-5 | CAS number: 149021-58-9
Toxicity to aquatic algae and cyanobacteria
Administrative data
Link to relevant study record(s)
Description of key information
In this 72-h growth inihibition test with Desmodesmus subspicatus the 72-h EC50 based on growth rate was determined as 84.9 mg/L and the overall NOEC as 10 mg/L. The test substance is acutely harmful to aquatic algae.
Key value for chemical safety assessment
- EC50 for freshwater algae:
- 84.9 mg/L
- EC10 or NOEC for freshwater algae:
- 10 mg/L
Additional information
Concerning the algal toxicity, a GLP algae growth inhibition test according to OECD guideline 201 and EU method C.3 with the algae Desmodesmus subspicatus was performed. The algae was exposed to test concentrations of 0 (control), 4.6, 10, 22, 46, 100 mg/L with 6 replicates for the control and 3 replicates for each test concentration. Due to the photolytical instability of 2-propylheptyl acrylate the test concentrations could not be quantified by analytical methods. No effects on algal growth or yield were observed in test groups with measured initial concentrations up to the water solubility limit of the test substance (10 mg/L nominal). All effects on algal growth occurred in test groups with measured initial concentrations greater than the water solubility limit of the test substance. It is likely that these observed effects were due to soluble minor contaminants associated with the test substance, and not to the test substance itself. The measured concentrations deviated markedly from the nominal concentrations; however, mean measured concentrations could not be calculated. According to OECD guideline 23, for tests with chemicals that can not be quantified by analytical methods at the concentrations causing effects, the effect concentration can be expressed based on the nominal concentrations. The results in this study are consistent with all validity criteria and the test is valid according to the guidelines used for the study. No deviations from test guidelines or other incidents occurred during the course of the reported test. Based on the growth rate the EC50 (72 h) was determined to be 84.9 mg/L. The NOEC based on the growth rate is 10 mg/L. [BASF SE 2009]
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