Registration Dossier
Registration Dossier
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EC number: 208-883-6 | CAS number: 544-92-3
Acute Toxicity: dermal
Administrative data
- Endpoint:
- acute toxicity: dermal
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 017
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 402 (Acute Dermal Toxicity)
- GLP compliance:
- yes
- Test type:
- standard acute method
- Limit test:
- yes
Test material
- Reference substance name:
- Copper cyanide
- EC Number:
- 208-883-6
- EC Name:
- Copper cyanide
- Cas Number:
- 544-92-3
- Molecular formula:
- CCuN
- IUPAC Name:
- λ¹-copper(1+) iminomethanide
Constituent 1
Test animals
- Species:
- rat
- Strain:
- Sprague-Dawley
- Sex:
- male/female
Administration / exposure
- Type of coverage:
- not specified
- Vehicle:
- not specified
- Duration of exposure:
- 24 hours
- Doses:
- 2000 mg/kg bw
- No. of animals per sex per dose:
- 5 animals/sex/dose
- Control animals:
- no
Results and discussion
Effect levels
- Key result
- Sex:
- male
- Dose descriptor:
- LD50
- Effect level:
- > 2 000 mg/kg bw
- Based on:
- test mat.
- Mortality:
- There was no mortality observed in the study.
- Clinical signs:
- other: No remarkable change related to test substance administration was shown in clinical signs.
- Gross pathology:
- No grossly visible findings were evident in the all animals.
Applicant's summary and conclusion
- Interpretation of results:
- GHS criteria not met
- Conclusions:
- Based on the results of this study, the approximate lethal dose of the test substance. Copper cyanide (Copper(I) cyanide), was greater than 2000 mg/kg bw in male and female rats under the conditions of this study.
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