Registration Dossier
Registration Dossier
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EC number: 208-883-6 | CAS number: 544-92-3
Endpoint summary
Administrative data
Description of key information
The key ecotoxicity values to assess the aquatic toxicity of the registered substance copper cyanide are as follow:
- Short-term toxicity to fish: 96h-LC50 = 0.62 mg/L (based on measured concentrations)
- Long-term toxicity to fish: 60d-NOEC = 2.2 ug/L = 0.0022 mg/L (read-across from a long-term study on copper chloride, lowest chronic NOEC)
- Short-term toxicity to aquatic invertebrates: 48h-EC50 = 0.21 mg/L (based on measured concentrations)
- Long-term toxicity to aquatic invertebrates: 21d-NOEC = 12.6 ug/L = 0.0126 mg/L (read-across from a long-term study on copper chloride)
- Toxicity to aquatic algae and cyanobacteria: 72h-EC50 = 89.1 ug/L = 0.089 mg/L (based on measured concentrations, lowest E(L)C50) and 72h-NOEC = 18.1 ug/L = 0.0181 mg/L
- Toxicity to microorganisms: 48h-NOEC = 3.6 - 3.8 mg/L (Read-across from a study on copper chloride).
Based on these results, the lowest acute E(L)C50 is below 1 mg/L and the lowest chronic NOEC value is below 0.1 mg/L (between 0.001 and 0.01 mg/L)
Additional information
CLP Classification proposal
It is proposed to compare submission substance dataset to CLP environmental criteria laid down in CLP Regulation (including 2nd Adaptation to Technical Progress, Com Reg No 286/2011).
Acute aquatic hazard: category 1. Reasoning: lowest E(L)C50 below 1 mg/L.
M-factor acute = 10 because the lowest E(L)C50 is between 0.01 and 0.1 mg/L
Chronic aquatic hazard: category 1. Reasoning: adequate chronic toxicity data are available, the substance is considered as not rapidly degradable and the lowest NOEC value is below 0.1 mg/L.
M-factor chronic = 10 because the lowest chronic NOEC is between 0.001 and 0.01 mg/L and copper cyanide is regarded as a non rapidly degradable substance.
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