Registration Dossier
Registration Dossier
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EC number: 700-567-0 | CAS number: 1231728-34-9
Endpoint summary
Administrative data
Description of key information
Additional information
Short-term toxicity to fish
In a static limit test conducted according to OECD Guideline 203 and EU Method C.1, Danio rerio was exposed to a nominal test substance concentration of 100 mg/L hexanoic acid, 3,5,5-trimethyl-, tin (2+) salt (2:1) (water accommodated fraction) over a period of 96 h under static conditions. DOC analysis showed that no loss of substance occurred during the exposure period. For the test organism neither mortality nor symptoms of toxicity were observed (96 h NOEC>=100 mg/L; 96 h LC50>100 mg/L nominal).
Short-term toxicity to aquatic invertebrates
In a study conducted according to OECD Guideline 202 and EU Method C.2, Daphnia magna were exposed to a nominal test substance concentration of 100 mg/L hexanoic acid, 3,5,5-trimethyl-, tin (2+)salt (2:1)(water accommodated fraction) over a period of 48 h under static conditions. DOC analysis showed that no loss of substance occurred during the exposure period. At the concentration tested no immobilisation of daphnids was observed (48 h NOEC>=100 mg/L; 48 h EC50>100 mg/L).
Toxicity to aquatic algae and cyanobacteria
In an algal growth inhibition test conducted according to OECD Guideline 201 (Alga, Growth Inhibition Test) and EU Method C.3 (Algal Inhibition test), cultures of Desmodesmus subspicatus were exposed to nominal test substance concentrations of 6.25, 12.5, 25, 50, and 100 mg/L hexanoic acid, 3,5,5-trimethyl-, tin (2+)salt (2:1) for 72 h under static conditions. The test substance concentrations were checked by DOC analysis at 0, 24, 48, and 72 h after application. The recovery of DOC in test solutions (25 -100 mg/L test substance) was in the range between 87 and 120% of nominal. For the parameter yield the EyC50 (0 -72 h) value was 44.7 mg/L and the LOEC and NOEC values were 50 and 25 mg/L, respectively, after 72 h of exposure. For the parameter growth rate the ErC50 (0 -72 h) value was 94.9 mg/L and the LOEC and NOEC values were 50 and 25 mg/L, respectively, after 72 h of exposure.
Toxicity to microorganisms
According to REACH Regulation (Annex VIII, 9.1.4, column II), the study on respiration inhibition of activated sludge does not need to be done if the substance is readily biodegradable. The test item proved to be readily biodegradable and is fulfilling the 10 d-window criterion. In the toxicity control of this study respiration inhibition was not observed.
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