Registration Dossier
Registration Dossier
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EC number: 271-347-5 | CAS number: 68541-50-4
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
No toxic effects up to the limit of water solubility (<0.05 mg/L)
Key value for chemical safety assessment
Additional information
Two GLP guideline studies on the acute toxicity of
2-ethyl-2-(((1-oxoisooctadecyl)oxy)methyl)-1,3-propanediyl bis
(isooctadecanoate) (CAS 68541-50-4) to fish are available. The key study
was conducted according to OECD guideline 203 (van Egmond, 1996). Zebra
fish (Brachydanio rerio) were exposed to the test substance in a
semi-static test system for 96 hours. The test solution was renewed
every 24 hours and the substance concentration was determined
analytically. At the end of the exposure period a LC50 > 48 mg/L (NOEC
>= 48 mg/L) was determined based on the measured substance concentration.
A second study on the acute toxicity of the substance was also
accomplished in a semi-static test system (Guhl, 1992). The study
followed guideline ISO 7346-1 and was conducted with Zebra fish (Danio
rerio) as test organisms. The fish were exposed to the substance for 96
hours. A LC50 > 10000 mg/L based on nominal test concentrations was
reported.
Based on the results of the acute toxicity tests toxic effects on fish are not expected up to the water solubility limit of the substance (<0.05 mg/L).
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