Sodium 4-vinylbenzenesulphonate

PBT assessment

PBT assessment: overall result

PBT status:

the substance is not PBT / vPvB

Justification:

The substance displays properties that indicate persistency within the environment, based on low ready biodegradability. Under the conditions of the ready biodegradation testing, 6% degradation occured indicating that the substance is not readily biodegradable. In addition, the substance is highly water soluble and stable to hydrolysis.

The substance is highly water soluble and does not tend to lipid tissues. The partition coefficient test has been measured to be log Pow of -3.44. The partition coefficient is significantly below 4.5 and could not scientifically justify conducting additional assessment for bioaccumulation testing. Furthermore, an estimation of the BCF has been undertaken according to the BCFBAF Program (v3.01) Arnot-Gobas BCF & BAF Methods in the EPI Suite. The BCF is estimated to be 3.162

The substance has been testing with three trophic species by acute exposure. On the basis of these data further assessment for long term toxicity is not scientifically justified due to a lack of response. The substance is highly water soluble and can therefore be considered to be bioavailable under the conditions of the tests. Since the measured EC50 values all exceed 1000mg/l the NOEC values can be predicted to exceed 0.1mg/l.

Data to directly assess the carcinogenicity are not available for the substance. There is however data available from three in vitro asssays which all give negative results. These data give no indication of mutagenicity and also give no indication that the substance is likely to carcinogenic. In addition, the screening reproductive toxicity data would suggest that the substance is not a reproductive toxin.

Data are available for the subacute oral toxicity of the substance. These data suggest that the substance is not unduly toxic and establishes a NOAEL at 300mg/l.

Likely routes of exposure:

Dermal