Registration Dossier
Registration Dossier
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EC number: 211-519-9 | CAS number: 657-27-2
Explosiveness
Administrative data
- Endpoint:
- explosiveness
- Type of information:
- other: statement
- Adequacy of study:
- supporting study
- Study period:
- 29 June 2010 - 03 August 2010
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: This study has been performed according to OECD and EC guideline and according to GLP principles. Based on the molecular structure a statement rather than a full study was considered sufficient to cover this endpoint.
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 010
- Report date:
- 2010
Materials and methods
Test guidelineopen allclose all
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.14 (Explosive properties)
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- other: United Nations (UN), UN no. ST/SG/AC.10/11/Rev.4: Recommendations on the Transport of Dangerous Goods, Part I: Classification Procedures, Test Methods and Criteria Relating to Explosives of Class 1, Section 13: “Test Series 3”, 2003.
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- other: United Nations (UN), UN no. ST/SG/AC.10/11/Rev.4: Recommendations on the Transport of Dangerous Goods, Appendix 6: “Screening Procedures”, 2003.
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
Test material
- Reference substance name:
- Lysine hydrochloride
- EC Number:
- 211-519-9
- EC Name:
- Lysine hydrochloride
- Cas Number:
- 657-27-2
- Molecular formula:
- C6H14N2O2.ClH
- IUPAC Name:
- lysine hydrochloride
- Details on test material:
- - Name of test material (as cited in study report): L-Lysine Monohydrochloride
- Molecular formula: C6H14N2O2HCl
- Molecular weight: 182.65
- Substance type: Beige powder with lumps
- Physical state: Solid
- Analytical purity: 99.72%
- Impurities (identity and concentrations): -
- Composition of test material, percentage of components: -
- Isomers composition: -
- Purity test date: -
- Lot/batch No.: 0148
- Expiration date of the lot/batch: 28 May 2012
- Stability under test conditions: Stable
- Storage condition of test material: At room temperature in the dark
- Other: -
Constituent 1
Results and discussion
Small-scale preliminary tests
- Parameter:
- other: The oxygen balance of the test substance was –153%, which is higher than –200%. The test substance does not contain chemical groups which are associated with explosive properties.
- Remarks on result:
- other:
- Remarks:
- The oxygen balance of the test substance was –153%, which is higher than –200%. The value is obtained due to the presence of an acid group and hydrochloric acid in the molecular structure of the test substance. These types of groups are not chemically instable or highly energetic. Based on this the test substance is considered to pose no risk for explodability. A test substance is considered explosive when it can react to produce very rapid increases in temperature or pressure. The test substance does not contain chemical groups which are associated with explosive properties.The molecular structures of impurities at <1% were not taken into account. In conclusion, L-Lysine Monohydrochloride has no explosive properties.
Any other information on results incl. tables
A test substance is considered explosive when it can react to produce very rapid increases in temperature or pressure.
The test substance does not contain chemical groups which are associated with explosive properties.The molecular structures of impurities at <1% were not taken into account.
The oxygen balance of the test substance was –153%, which is higher than –200%. The value is obtained due to the presence of an acid group and hydrochloric acid in the molecular structure of the test substance. These types of groups are not chemically instable or highly energetic. Based on this the test substance is considered to pose no risk for explodability.
In conclusion, L-Lysine Monohydrochloride has no explosive properties.
Applicant's summary and conclusion
- Interpretation of results:
- GHS criteria not met
- Conclusions:
- L-Lysine Monohydrochloride has no explosive properties.
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