Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
skin sensitisation
Remarks:
in vivo
Type of information:
calculation (if not (Q)SAR)
Remarks:
Migrated phrase: estimated by calculation
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Cross-reference
Reason / purpose for cross-reference:
reference to same study

Data source

Reference
Reference Type:
other: Authoritative data base
Title:
CAS No.: 98-43-1
Author:
Danish EPA Model
Year:
2012
Bibliographic source:
QSAR predictions by Danish Environmental Protection Agency (EPA)model powered by OASIS database

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
other:
Principles of method if other than guideline:
Estimation database
GLP compliance:
no
Type of study:
not specified

Test material

Constituent 1
Chemical structure
Reference substance name:
4-sulphoanthranilic acid
EC Number:
202-668-0
EC Name:
4-sulphoanthranilic acid
Cas Number:
98-43-1
Molecular formula:
C7H7NO5S
IUPAC Name:
2-amino-4-sulfobenzoic acid

In vivo test system

Test animals

Strain:
not specified
Sex:
not specified

Study design: in vivo (non-LLNA)

Induction
Vehicle:
no data
Challenge
Vehicle:
no data

Results and discussion

In vivo (non-LLNA)

Results
Reading:
1st reading
Group:
test chemical
Clinical observations:
not sensitising to skin.
Remarks on result:
other: Reading: 1st reading. Group: test group. Clinical observations: not sensitising to skin..

In vivo (LLNA)

Results
Parameter:
SI
Remarks on result:
other: no data

Any other information on results incl. tables

Non sensiting to skin as per the estimation database

Applicant's summary and conclusion

Interpretation of results:
not sensitising
Remarks:
Migrated information Criteria used for interpretation of results: EU
Executive summary:

4-sulphoanthranilic acid is not sensitising to skin.