Registration Dossier

Diss Factsheets

Administrative data

Endpoint:
toxicity to microorganisms
Type of information:
calculation (if not (Q)SAR)
Remarks:
Migrated phrase: estimated by calculation
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Cross-reference
Reason / purpose for cross-reference:
reference to same study

Data source

Reference
Reference Type:
other: Authoritative data base
Title:
CAS No.: 98-43-1
Author:
Danish EPA Model
Year:
2012
Bibliographic source:
QSAR predictions by Danish Environmental Protection Agency (EPA)model powered by OASIS database;DK-EPA

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
other:
Principles of method if other than guideline:
Multicase model is used to estimate IGC50 (46h) of tetrahymena pyriformis.
GLP compliance:
no

Test material

Constituent 1
Chemical structure
Reference substance name:
4-sulphoanthranilic acid
EC Number:
202-668-0
EC Name:
4-sulphoanthranilic acid
Cas Number:
98-43-1
Molecular formula:
C7H7NO5S
IUPAC Name:
2-amino-4-sulfobenzoic acid

Test solutions

Vehicle:
not specified

Test organisms

Test organisms (species):
Tetrahymena pyriformis

Study design

Test type:
not specified
Water media type:
not specified
Total exposure duration:
46 h

Results and discussion

Effect concentrations
Duration:
46 h
Dose descriptor:
other: IG50
Effect conc.:
404.445 mg/L
Nominal / measured:
estimated
Conc. based on:
test mat.
Basis for effect:
not specified

Applicant's summary and conclusion

Executive summary:

4-sulphoanthranilic acid found to be toxic to microorganism at IG50 404.4453 mg/L.