Registration Dossier

Physical & Chemical properties

Partition coefficient

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Administrative data

Endpoint:
partition coefficient
Type of information:
migrated information: read-across from supporting substance (structural analogue or surrogate)
Adequacy of study:
key study
Study period:
2012
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: The study has been carried out accordin to OECD testing guidelines.

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2012

Materials and methods

Test guideline
Qualifier:
according to
Guideline:
OECD Guideline 107 (Partition Coefficient (n-octanol / water), Shake Flask Method)
Deviations:
no
GLP compliance:
no
Type of method:
shake-flask method to: flask method
Partition coefficient type:
octanol-water

Test material

Reference
Name:
Unnamed
Type:
Constituent
Test material form:
solid: particulate/powder
Remarks:
migrated information: powder

Results and discussion

Partition coefficient
Type:
log Pow
Partition coefficient:
3.38
Temp.:
20 °C
pH:
6

Applicant's summary and conclusion

Conclusions:
The experimental logPow of ursodeoxycholic acid at 20° C is 3.38.
Executive summary:

According to the OECD guideline 107 method, the expermental logPow of ursodeoxycholic acid at 20° C is 3.38.