Registration Dossier

Administrative data

Endpoint:
explosiveness
Type of information:
migrated information: read-across from supporting substance (structural analogue or surrogate)
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: The study has been carried out according to Council Regulation (EC) No 440/2008 of 30 May 2008, Part A: Methods for the Determination of Physico-Chemical Properties: A. 14 “Explosive Properties” .

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2012

Materials and methods

Test guideline
Qualifier:
according to
Guideline:
EU Method A.14 (Explosive properties)
Deviations:
no
GLP compliance:
no

Test material

Reference
Name:
Unnamed
Type:
Constituent
Test material form:
solid: particulate/powder
Remarks:
migrated information: powder

Results and discussion

Small-scale preliminary testsopen allclose all
Parameter:
other: More sensitive to shock than m-dinitrobenzene
Remarks:
migrated information
Remarks on result:
other: no data
Remarks:
No explosion was obtained in sensitivity tests
Parameter:
other: More sensitive to friction than m-dinitrobenzene
Remarks:
migrated information
Remarks on result:
other: no data
Remarks:
No explosion was obtained in sensitivity tests
Parameter:
other: Explosive under influence of flame
Remarks:
migrated information
Remarks on result:
negative (not further specified)
Parameter:
other: Explosive (not specified)
Remarks:
migrated information
Remarks on result:
negative (not further specified)

Applicant's summary and conclusion

Interpretation of results:
non explosive
Remarks:
Migrated information
Conclusions:
Ursodeoxycholic acid is not explosive.
Executive summary:

From experimental data it can be concluded that ursodeoxycholic acid did not present explosive properties.