Registration Dossier

Administrative data

Key value for chemical safety assessment

Additional information

Methyl 3-α,7-α-diacetoxy-12-oxo-5-β-cholan-24-oate is NOT MUTAGEN.


Justification for selection of genetic toxicity endpoint
Mutagenicity was estimated employing QSAR predictors and decision rule systems, in order to apply a consensus approach and improve the reliability of the predictions.

Endpoint Conclusion: No adverse effect observed (negative)

Justification for classification or non-classification

According to regulation 1272/2008/EC, methyl 3-α,7-α-diacetoxy-12-oxo-5-β-cholan-24-oate is not classified for the mutagenicity.