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Toxicological information

Developmental toxicity / teratogenicity

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Administrative data

Endpoint:
developmental toxicity
Type of information:
(Q)SAR
Adequacy of study:
supporting study
Reliability:
2 (reliable with restrictions)
Justification for type of information:
QSAR prediction: migrated from IUCLID 5.6

Data source

Reference
Reference Type:
publication
Title:
Developmental Toxicity
Author:
Developmental Toxicity model (CAESAR) (version 2.1.6)
Bibliographic source:
VEGA NIC (version 2.1.8)
Report date:
2013

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
other: General model for estimating the development toxicity
Principles of method if other than guideline:
no data
GLP compliance:
no
Limit test:
no

Test material

Constituent 1
Chemical structure
Reference substance name:
o-phenethylbenzoic acid
EC Number:
225-511-8
EC Name:
o-phenethylbenzoic acid
Cas Number:
4890-85-1
Molecular formula:
C15H14O2
IUPAC Name:
2-(2-phenylethyl)benzoic acid
Test material form:
solid: particulate/powder
Remarks:
migrated information: powder

Results and discussion

Results: maternal animals

Maternal developmental toxicity

Details on maternal toxic effects:
Maternal toxic effects:no data

Effect levels (maternal animals)

Dose descriptor:
other: qualitative result by model
Based on:
test mat.
Basis for effect level:
other: developmental toxicity

Results (fetuses)

Details on embryotoxic / teratogenic effects:
Embryotoxic / teratogenic effects:no data

Fetal abnormalities

Abnormalities:
not specified

Overall developmental toxicity

Developmental effects observed:
not specified

Any other information on results incl. tables

Model assessment: Prediction is Toxicant and the result appears reliable.

Details are provided in attachment on the section: "attached full study report".

Applicant's summary and conclusion

Conclusions:
The prediction of the model is toxicant and the result appears reliable.