Registration Dossier
Registration Dossier
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EC number: 225-511-8 | CAS number: 4890-85-1
Genetic toxicity: in vitro
Administrative data
- Endpoint:
- genetic toxicity in vitro
- Remarks:
- Type of genotoxicity: other: not applicable
- Type of information:
- (Q)SAR
- Adequacy of study:
- disregarded due to major methodological deficiencies
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- other: The study results are disregarded as the substance is out of the the Applicability Domain (AD) of the model.
- Justification for type of information:
- QSAR prediction: migrated from IUCLID 5.6
Data source
Reference
- Reference Type:
- publication
- Title:
- Mutagenicity
- Author:
- U.S. Environmental Protection
- Bibliographic source:
- T.E.S.T. v.4.1
- Report date:
- 2013
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- other: General model for estimating the mutagenicity
- Principles of method if other than guideline:
- no data
- GLP compliance:
- no
- Type of assay:
- other: QSAR
Test material
- Reference substance name:
- o-phenethylbenzoic acid
- EC Number:
- 225-511-8
- EC Name:
- o-phenethylbenzoic acid
- Cas Number:
- 4890-85-1
- Molecular formula:
- C15H14O2
- IUPAC Name:
- 2-(2-phenylethyl)benzoic acid
- Test material form:
- solid: particulate/powder
- Remarks:
- migrated information: powder
Constituent 1
Results and discussion
Test results
- Species / strain:
- not specified
- Metabolic activation:
- not specified
- Genotoxicity:
- negative
- Cytotoxicity / choice of top concentrations:
- not specified
- Remarks on result:
- other: other: not applicable
- Remarks:
- Migrated from field 'Test system'.
Any other information on results incl. tables
Model assessment: Prediction is "mutagenicity = negative", but the result may be not reliable as only moderately similar compounds with known experimental value in the training set have been found.
Applicant's summary and conclusion
- Conclusions:
- Interpretation of results (migrated information):
negative
The obtained results are disregarded as the substance is out from the applicability domain of the model.
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