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Physical & Chemical properties

Water solubility

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Administrative data

Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2012
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: guideline study according to GLP principles

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2012
Report Date:
2012

Materials and methods

Test guidelineopen allclose all
Qualifier:
according to
Guideline:
OECD Guideline 105 (Water Solubility)
Deviations:
no
Qualifier:
according to
Guideline:
EU Method A.6 (Water Solubility)
Deviations:
no
GLP compliance:
yes (incl. certificate)
Type of method:
flask method

Test material

Reference
Name:
Unnamed
Type:
Constituent

Results and discussion

Water solubilityopen allclose all
Water solubility:
> 500 g/L
Temp.:
20 °C
pH:
4
Water solubility:
> 500 g/L
Temp.:
20 °C
pH:
7
Water solubility:
> 500 g/L
Temp.:
20 °C
pH:
9
Details on results:
Preliminary test results showes a solubility of > 1000 g/l.
In the main test three pH values was performed with five different test ite, concentrations in the resepective buffers. No correction of the pH values was performed. The mixtrure were incubated for approx. 24 h at 30 °C (300 rpm) and then equilibrated at 20 °C for 24 h. No phase sepration was oberved. The test item was completely dissolved in all samples. The pH values were checked.

Applicant's summary and conclusion

Conclusions:
Interpretation of results (migrated information): very soluble (> 10000 mg/L)
The result of water solubility shows >500 g/L at 20°C and at pH 4, 7 and 9