Registration Dossier
Registration Dossier
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EC number: 212-001-5 | CAS number: 736-30-1
Skin sensitisation
Administrative data
- Endpoint:
- skin sensitisation
- Remarks:
- other: QSAR
- Type of information:
- (Q)SAR
- Adequacy of study:
- supporting study
- Reliability:
- 3 (not reliable)
- Rationale for reliability incl. deficiencies:
- other: DEREK is predominantly designed to predict the presence rather than the absence of structural alerts and its associated toxic properties.
- Justification for type of information:
- QSAR prediction: migrated from IUCLID 5.6
Data source
Reference
- Reference Type:
- other: QSAR Prdiction
- Title:
- Unnamed
- Year:
- 2 014
- Report date:
- 2014
Materials and methods
- Principles of method if other than guideline:
- DEREK prediction of skin sensitisation potential based on expert rules
- GLP compliance:
- no
- Type of study:
- other: QSAR
Test material
- Reference substance name:
- 1,1'-ethane-1,2-diylbis(4-nitrobenzene)
- EC Number:
- 212-001-5
- Cas Number:
- 736-30-1
- Molecular formula:
- C14H12N2O4
- IUPAC Name:
- 1,1'-ethane-1,2-diylbis(4-nitrobenzene)
Constituent 1
Results and discussion
Applicant's summary and conclusion
- Interpretation of results:
- not sensitising
- Remarks:
- Migrated information Criteria used for interpretation of results: expert judgment
- Conclusions:
- According to the DEREK prediction the structure suggests no skin sensitizing properties.
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