Registration Dossier
Registration Dossier
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EC number: 607-088-5 | CAS number: 224785-90-4
Toxicity to aquatic algae and cyanobacteria
Administrative data
Link to relevant study record(s)
- Endpoint:
- toxicity to aquatic algae and cyanobacteria
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- December 2013
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 201 (Alga, Growth Inhibition Test)
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Analytical monitoring:
- yes
- Vehicle:
- no
- Test organisms (species):
- Desmodesmus subspicatus (previous name: Scenedesmus subspicatus)
- Test type:
- static
- Water media type:
- freshwater
- Limit test:
- yes
- Total exposure duration:
- 72 h
- Duration:
- 72 h
- Dose descriptor:
- EC50
- Effect conc.:
- > 8.49 mg/L
- Nominal / measured:
- meas. (initial)
- Conc. based on:
- test mat.
- Basis for effect:
- growth rate
- Remarks on result:
- other: saturated solution
- Validity criteria fulfilled:
- yes
- Conclusions:
- The EC50/72 h is higher than a saturated solution with 8.49 mg/L. However, the toxicity threshold for algae is below 8.49 mg/L, since the inhibition of growth reached 31% at the highest concentration tested.
- Executive summary:
Algae Desmodesmus subspicatus were incubated with the test material in a limit test over aperiod of 72 h. The test substance concentrations were 0.09, 0.85, and 8.49 mg/L. The test cocentrations were a saturated solution prepared by suspending 100 mg/L and stirring for 24 h, and dilutions of 1:10 and 1:100 thereof.
The growth was inhibited at the hihgest concentration to 31%. Thus, the EC50 is higher than a saturated solution (8.49 mg/L), but the toxicity threshold for algal growth inhibition is below a saturated solutiuon. The NOEC was 0.68 mg/L.
Reference
Description of key information
The EC50/72 h is higher than a saturated solution with 8.49 mg/L. However, the toxicity threshold for algae is below 8.49 mg/L, since the inhibition of growth reached 31% at the highest concentration tested.
Key value for chemical safety assessment
- EC50 for freshwater algae:
- 8.49 mg/L
Additional information
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