Registration Dossier
Registration Dossier
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EC number: 700-857-7 | CAS number: -
Endpoint summary
Administrative data
Description of key information
In two skin irritation studies in rabbits conducted according to or similar to the OECD guideline 404, the substance was found to be not irritating or moderately irritating but is not classified according to the criteria of Annex VI to the Directive 67/548/EEC and CLP Regulation (EC) N° (1272-2008).
No data are available for eye irritation but the substance is a strong acid (pH<2.0).
Key value for chemical safety assessment
Skin irritation / corrosion
Endpoint conclusion
- Endpoint conclusion:
- adverse effect observed (irritating)
Eye irritation
Endpoint conclusion
- Endpoint conclusion:
- adverse effect observed (irritating)
Additional information
In two skin irritation studies in rabbits, the substance was found to be not irritating or moderately irritating but is not classified according to the criteria of Annex VI to the Directive 67/548/EEC and CLP Regulation (EC) N° (1272-2008).
No data are available for eye irritation but the substance is a strong acid (pH<2.0) and the acid reserve is 14 g NaOH/100 g of substance (see file attached), which could lead to serious damages to the eyes. Therefore, the substance is classified as risk of serious damage to eyes (R41) according to the Directive 67/548/EEC and causes serious eye damage (H318) according to the CLP Regulation (EC) N° (1272-2008).
Effects on skin irritation/corrosion: slightly irritating
Effects on eye irritation: highly irritating
Effect level: empty Endpoint conclusion: Adverse effect observed
Justification for classification or non-classification
In two skin irritation studies in rabbits, the substance was found to be not irritating or moderately irritating but is not classified according to the criteria of Annex VI to the Directive 67/548/EEC and CLP Regulation (EC) N° (1272-2008).
No data are available for eye irritation but the substance is a strong acid (pH<2.0) and the acid reserve is 14 g NaOH/100 g of substance (see file attached), which could lead to serious damages to the eyes. Therefore, the substance is classified as risk of serious damage to eyes (R41) according to the Directive 67/548/EEC and causes serious eye damage (H318) according to the CLP Regulation (EC) N° (1272-2008).
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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