Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Environmental fate & pathways

Additional information on environmental fate and behaviour

Currently viewing:

Administrative data

Endpoint:
additional information on environmental fate and behaviour
Type of information:
other: handbook data
Adequacy of study:
supporting study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: handbook with reliable values

Data source

Reference
Reference Type:
review article or handbook
Title:
Health effects of magnesium in water
Author:
Lenntech organization
Year:
1993
Bibliographic source:
http://www.lenntech.com/periodic/water/magnesium/magnesium-and-water.htm

Materials and methods

Test guideline
Qualifier:
no guideline followed
GLP compliance:
not specified
Type of study / information:
health effects of magnesium in water

Test material

Constituent 1
Chemical structure
Reference substance name:
Magnesium
EC Number:
231-104-6
EC Name:
Magnesium
Cas Number:
7439-95-4
Molecular formula:
Mg
IUPAC Name:
magnesium
Test material form:
solid: compact

Results and discussion

Any other information on results incl. tables

The human body contains about 25 g of magnesium, of which 60% is present in the bones and 40% is present in muscles and other tissue. It is a dietary mineral for humans, one of the micro elements that are responsible for membrane function, nerve stimulant transmission, muscle contraction, protein construction and DNA replication. Magnesium is an ingredient of many enzymes. Magnesium and calcium often perform the same functions within the human body and are generally antagonistic.

There are no known cases of magnesium poisoning. At large oral doses magnesium may cause vomiting and diarrhoea. High doses of magnesium in medicine and food supplements may cause muscle slackening, nerve problems, depressions and personality changes.
As was mentioned before, it is unusual to introduce legal limits for magnesium in drinking water, because there is no scientific evidence of magnesium toxicity. In other compounds, for example asbestos, magnesium may be harmful.

Applicant's summary and conclusion

Conclusions:
The human body contains about 25 g of magnesium, of which 60% is present in the bones and 40% is present in muscles and other tissue. It is a dietary mineral for humans, one of the micro elements that are responsible for membrane function, nerve stimulant transmission, muscle contraction, protein construction and DNA replication. Magnesium is an ingredient of many enzymes. Magnesium and calcium often perform the same functions within the human body and are generally antagonistic.
Executive summary:

The human body contains about 25 g of magnesium, of which 60% is present in the bones and 40% is present in muscles and other tissue. It is a dietary mineral for humans, one of the micro elements that are responsible for membrane function, nerve stimulant transmission, muscle contraction, protein construction and DNA replication. Magnesium is an ingredient of many enzymes. Magnesium and calcium often perform the same functions within the human body and are generally antagonistic.

There are no known cases of magnesium poisoning. At large oral doses magnesium may cause vomiting and diarrhoea. High doses of magnesium in medicine and food supplements may cause muscle slackening, nerve problems, depressions and personality changes.
As was mentioned before, it is unusual to introduce legal limits for magnesium in drinking water, because there is no scientific evidence of magnesium toxicity. In other compounds, for example asbestos, magnesium may be harmful.