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Diss Factsheets

Physical & Chemical properties

Stability in organic solvents and identity of relevant degradation products

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Administrative data

Link to relevant study record(s)

Reference
Endpoint:
stability in organic solvents and identity of relevant degradation products
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2010
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Acceptable, well-documented study report which meets basic scientific principles.
Principles of method if other than guideline:
Stability in organic solvents by UV-vis spectrometry
Test substance stable:
yes

The test substance is stable and homogeneous for 24 hours in DMSO (0.1 and 50 mg/mL) at room temperature and for more than 72 hours in 1,2-propylene glycol (0.1 and 50 mg/mL) at room temperature.

Intensive stirring is necessary.

Conclusions:
The test substance is stable and homogeneous for 24 hours in DMSO (0.1 and 50 mg/mL) at room temperature and for more than 72 hours in 1,2-propylene glycol (0.1 and 50 mg/mL) at room temperature.
Executive summary:

The stability of the test substance in organic solvents was determined by UV-vis spectrometry.

The test substance is stable and homogeneous for 24 hours inDMSO (0.1 and 50 mg/mL) at room temperature and for more than 72 hours in 1,2-propylene glycol (0.1 and 50mg/mL) at room temperature.

Description of key information

The test substance is stable and homogeneous for 24 hours in DMSO (0.1 and 50 mg/mL) at room temperature and for more than 72 hours in 1,2-propylene glycol (0.1 and 50 mg/mL) at room temperature.

Additional information