Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 211-720-1 | CAS number: 691-37-2
PBT assessment
Administrative data
PBT assessment: overall result
- PBT status:
- the substance is not PBT / vPvB
- Justification:
Persistence Assessment
4-methylpent-1-ene does not meet the criteria for ready biodegradation, based on the results of the aerobic biodegradation screening tests (e.g. 1% degradation in the OECD 301 modified MITI test). Furthermore, the substance has a half-life in fresh water that is higher than 40 days (e.g. >1 year at 25°C in the OECD 111, hydrolysis as a function of pH). In conclusion, 4-methylpent-1-ene has the potential to fulfill the criteria for persistency as outlined in Annex XIII of the REACH legislation of December 2006.
Bioaccumulation Assessment
According to Annex XIII of Regulation (EC) No 1907/2006 and to the Guidance on information requirements and chemical safety assessment Chapter R.11 (PBT Assessment, May 2008), a substance does not fulfill the criterion “bioaccumulative (B)” or “very bioaccumulative (vB)” if the BCF is below 2000 respectively 5000 or the log Kow is below 4.5.
4-methylpent-1-ene has a log Kow of the than this (log Kow = 3.38), which indicates that 4-methylpent-1-ene does not have the potential for bioconcentration in aquatic organisms. Therefore it does not fulfill the criteria for bioaccumulation as outlined in Annex XIII of REACH legislation of December 2006.
Toxicity Assessment
According to Annex XIII of Regulation (EC) No 1907/2006 and according to the Guidance on information requirements and chemical safety assessment Chapter 11 (PBT Assessment, May 2008), a substance does not fulfill the criterion if the NOEC for marine or freshwater organisms is higher than 0.01mg/l and if there is no evidence of chronic toxicity considering human health and no classification as carcinogenic (category1 or 2), mutagenic (category 1or 2) or toxic for reproduction (category 1, 2 or 3) according to Directive 67/548/ECC.
Measured aquatic toxicity data indicate that 4-methylpent-1-ene presents a low toxicity hazard to aquatic species. All EC50/LC50 values (fish, daphnia and algae) are greater than 0.01 mg/l.
Furthermore, 4-methylpent-1-ene is not classified as carcinogenic (category 1A or 1B), germ cell mutagenic (category 1A or 1B), or toxic for reproduction (category 1A, 1B or 2) and there is no evidence of chronic toxicity, as identified by the classifications STOT (repeated exposure), category 1(oral, dermal, inhalation of gases/vapours, inhalation of dust/mist/fume) or category 2 (oral, dermal, inhalation of gases/vapours, inhalation of dust/mist/fume) according to Regulation (EC) No 1272/2008.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
