Registration Dossier
Registration Dossier
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EC number: 203-818-8 | CAS number: 110-95-2
Ecotoxicological Summary
Administrative data
Hazard for aquatic organisms
Freshwater
- Hazard assessment conclusion:
- PNEC aqua (freshwater)
- PNEC value:
- 8.8 µg/L
- Assessment factor:
- 50
- PNEC freshwater (intermittent releases):
- 0.1 mg/L
Marine water
- Hazard assessment conclusion:
- PNEC aqua (marine water)
- PNEC value:
- 0.88 µg/L
- Assessment factor:
- 500
STP
- Hazard assessment conclusion:
- PNEC STP
- PNEC value:
- 100 mg/L
- Assessment factor:
- 10
Sediment (freshwater)
- Hazard assessment conclusion:
- PNEC sediment (freshwater)
- PNEC value:
- 0.13 mg/kg sediment dw
- Extrapolation method:
- equilibrium partitioning method
Sediment (marine water)
- Hazard assessment conclusion:
- PNEC sediment (marine water)
- PNEC value:
- 0.013 mg/kg sediment dw
- Extrapolation method:
- equilibrium partitioning method
Hazard for air
Air
- Hazard assessment conclusion:
- no hazard identified
Hazard for terrestrial organisms
Soil
- Hazard assessment conclusion:
- PNEC soil
- PNEC value:
- 0.021 mg/kg soil dw
- Extrapolation method:
- assessment factor
Hazard for predators
Secondary poisoning
- Hazard assessment conclusion:
- no potential for bioaccumulation
Additional information
Conclusion on classification
The information concerning the aquatic toxicity of Tetramethyltrimethylenediamine (TMPDA) are summarized hereafter:
Acute toxicity to fish: LC50_96h > 100 mg/L
Acute toxicity to daphnia: EC50_48h = 52.8 mg/L
Long-term toxicity to daphnia: NOEC = 0.44 mg/LToxicity to algae: ErC50_72h = 10 mg/L and ErC10_72h = 1.1 mg/L
TMPDA is not readily biodegradable and has a log Kow < 1.
Based on these results, here is the classification for TMPDA:
Dangerous substance directive: R51/53
Classification Labelling & Packaging: H411 (Chronic 2)
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