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Diss Factsheets

Physical & Chemical properties

Solubility in organic solvents / fat solubility

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Administrative data

Link to relevant study record(s)

Reference
Endpoint:
solubility in organic solvents / fat solubility
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
comparable to guideline study
Justification for type of information:
Experimental test result performed using standard OECD test guidelines.
Qualifier:
according to guideline
Guideline:
other: as mentioned below
Principles of method if other than guideline:
The solubility determination of test substance in various organic solvents was done with acetone, acetonitrile, methanol, ethanol, toluene and Dimethylformamide (DMF).
GLP compliance:
not specified
Key result
Medium:
acetone
Solubility:
> 1 000 g/L
Remarks on result:
other: highly soluble
Key result
Medium:
acetonitrile
Solubility:
> 1 000 g/L
Remarks on result:
other: highly soluble
Key result
Medium:
methanol
Solubility:
> 1 000 g/L
Remarks on result:
other: highly soluble
Key result
Medium:
ethanol
Solubility:
> 1 000 g/L
Remarks on result:
other: highly soluble
Key result
Medium:
toluene
Solubility:
> 1 000 g/L
Remarks on result:
other: highly soluble
Key result
Medium:
dimethylformamide
Solubility:
> 1 000 g/L
Remarks on result:
other: highly soluble
Conclusions:
The solubility range of the substance mixture of test substance was determined to be greater than 1000 g/l.
Executive summary:

The solubility determination of test substance in various organic solvents was done with acetone, acetonitrile, methanol, ethanol, toluene and Dimethylformamide (DMF). The solubility of the test substance in acetone, acetonitrile, methanol, ethanol, toluene and Dimethylformamide (DMF) was determined to be greater than 1000 g/l. Hence, the substance was determined to be highly soluble in all the organic solvents tested.

Description of key information

The solubility determination of test substance in various organic solvents was done with acetone, acetonitrile, methanol, ethanol, toluene and Dimethylformamide (DMF). The solubility of the test substance in acetone, acetonitrile, methanol, ethanol, toluene and Dimethylformamide (DMF) was determined to be greater than 1000 g/l. Hence, the substance was determined to be highly soluble in all the organic solvents tested.

Key value for chemical safety assessment

Solubility in mg/100g standard fat:
1 000

Additional information

The solubility determination of test substance in various organic solvents was done with acetone, acetonitrile, methanol, ethanol, toluene and Dimethylformamide (DMF). The solubility of the test substance in acetone, acetonitrile, methanol, ethanol, toluene and Dimethylformamide (DMF) was determined to be greater than 1000 g/l. Hence, the substance was determined to be highly soluble in all the organic solvents tested.