Registration Dossier

Administrative data

Endpoint:
basic toxicokinetics
Type of information:
other: theoretical approach
Adequacy of study:
key study
Study period:
November 2010
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: Study is based on expert judgment.

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2010
Report Date:
2010

Materials and methods

Objective of study:
other: toxicokinetic assessment
Principles of method if other than guideline:
A theoretical approach of the toxicokinetic properties of the substance based on the available physico-chemical properties and toxicological data.

Test material

Reference
Name:
Unnamed
Type:
Constituent
Details on test material:
- Name of test material (as cited in study report): Silicic acid(H2Si2O5), barium salt(1:1), lead-doped
- Substance type: white powder
- Physical state: powder
- Purity: 100%
- Stability under test conditions: Stable
- Storage condition of test material: At room temperature in the dark

Results and discussion

Applicant's summary and conclusion

Conclusions:
Interpretation of results (migrated information): bioaccumulation potential cannot be judged based on study results
For risk assessment purposes the below values are proposed:
oral absorption factor: 50%
dermal absorption factor: 50%
inhalation absorption factor: 100%