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Physical & Chemical properties

Solubility in organic solvents / fat solubility

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Administrative data

Endpoint:
solubility in organic solvents / fat solubility
Type of information:
experimental study
Adequacy of study:
supporting study
Study period:
2009
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: The study was performed according to OECD 105 Guideline (adapted for n-Octanol)

Data source

Referenceopen allclose all

Reference Type:
study report
Title:
Unnamed
Year:
2009
Report date:
2009
Reference Type:
other company data
Title:
Unnamed
Report date:
2010

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
other: OECD 105
Deviations:
yes
Remarks:
adapted for n-Octanol
Principles of method if other than guideline:
For substances that are completely miscible with octanol, the numerical value of the octanol solubility should be derived from the density. Together with the water solubility this can be used to estimate logP values. The method is not applicable to substances that are completely miscible with both water and octanol.
GLP compliance:
no

Test material

Constituent 1
Chemical structure
Reference substance name:
(Z)-octadec-9-enylamine
EC Number:
204-015-5
EC Name:
(Z)-octadec-9-enylamine
Cas Number:
112-90-3
Molecular formula:
CH3(CH2)7CH=CH(CH2)7CH2NH2
IUPAC Name:
octadec-9-en-1-amine
Details on test material:
- Name of test material (as cited in study report):Oleylamine

Results and discussion

Solubility in organic solvents / fat solubility
Key result
Medium:
n-octanol
Solubility:
813 g/L
Temp.:
25 °C
Remarks on result:
other: since the substance is miscible at every ratio, the solubility is presented as the density of the pure substance
Test substance stable:
yes
Details on results:
Solubility of octadec-9-en-1-amine in n-octanol is 813 g/L.

Any other information on results incl. tables

Following mixtures of oleylamine and n-octanol were prepared at room temperature (23 °C):

10 ml n-octanol + 1 ml oleylamine: clear solution

10 ml n-octanol + 10 ml oleylamine: clear solution

5 ml n-octanol + 10 ml oleylamine: clear solution

1 ml n-octanol + 10 ml oleylamine: clear solution

Applicant's summary and conclusion

Conclusions:
From this result it can be concluded that oleylamine and n-octanol are miscible at every ratio. Thus, the density is used as the maximum solubility in n-Octanol.

The thermodynamics of solutions usually works with concentrations expressed as amount of substance per unit volume of solution. In the case of complete miscibility, the maximum concentration is the pure substance. As a result the numerical value of the solubility is given by the density expressed in g/L.
Executive summary:

The solubility of the test substance tetradecylamine in n-octanol was determined according to the OECD TG 105, using the shake-flask method. Solubility in n-octanol is 813 g/L.