Registration Dossier
Registration Dossier
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EC number: 204-635-6 | CAS number: 123-56-8
Acute Toxicity: oral
Administrative data
- Endpoint:
- acute toxicity: oral
- Type of information:
- experimental study
- Adequacy of study:
- weight of evidence
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- data from handbook or collection of data
Data source
Reference
- Reference Type:
- publication
- Title:
- Succinimida
- Author:
- Prous J. R.
- Year:
- 1 974
- Bibliographic source:
- Medicamentos de Actualidad, Vol. 10:224
Materials and methods
- Principles of method if other than guideline:
- Acute oral toxicity study in rats
- GLP compliance:
- not specified
- Test type:
- other: not specified
Test material
- Reference substance name:
- Succinimid
- IUPAC Name:
- Succinimid
- Details on test material:
- - Name: Succinimid (German)
- Amount: 50 g
- Storage of the test substance: 4°C
Constituent 1
Test animals
- Species:
- rat
- Strain:
- not specified
- Sex:
- not specified
- Details on test animals or test system and environmental conditions:
- not specified
Administration / exposure
- Route of administration:
- oral: unspecified
- Vehicle:
- not specified
- Details on oral exposure:
- not specified
- Doses:
- not specified
- No. of animals per sex per dose:
- not specified
- Control animals:
- not specified
- Details on study design:
- not specified
- Statistics:
- not specified
Results and discussion
Effect levels
- Key result
- Sex:
- not specified
- Dose descriptor:
- LD50
- Effect level:
- 14 000 mg/kg bw
- Based on:
- test mat.
- Mortality:
- not specified
- Clinical signs:
- other: not specified
- Gross pathology:
- not specified
- Other findings:
- not specified
Applicant's summary and conclusion
- Interpretation of results:
- GHS criteria not met
- Conclusions:
- In an acute oral toxicity in rats, an LD50 value of 14 g/kg bw was determined.
- Executive summary:
In an acute oral toxicity in rats, an LD50 value of 14 g/kg bw was determined.
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