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Ecotoxicological information

Short-term toxicity to fish

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Description of key information

In a GLP-Study according to OECD test guideline 203, the registered substance did not induce any mortality in fish at a loading level of 4 mg/L.

Key value for chemical safety assessment

LC50 for freshwater fish:
4 mg/L

Additional information

For the registered substance, one short-term fish toxicity study was available. As this study was conducted under GLP-conditions according to an OECD test guideline it was considered as Klimisch 1.

The acute toxicity of the the registered substance to fish ( zebrafish) was determined according to OECD-Guideline for Testing of Chemicals No. 203 ( 1992). A static limit test with a water accommodated fraction was conducted. The preparation method has been chosen with regard to the test item properties and in accordance with the relevant OECD guidance document (2000). Duration of the test was 96 h. Seven fish were exposed to the water accommodated fraction and the control. Water quality parameters pH-value, temperature and oxygen-saturation measured after 0, 24, 48, 72 and 96 h were determined to be within the acceptable limits. Specific test item analysis of the test media was carried out via GC-MS. Effects are given as nominal loading level (LL). As no mortality was observed at a loading level of 4 mg/L, the NOEL (no observed effect loading) as well as the LL50 are greater than 4 mg/L. (Cognis, 2006)