Registration Dossier
Registration Dossier
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EC number: 485-390-4 | CAS number: -
Toxicity to aquatic algae and cyanobacteria
Administrative data
Link to relevant study record(s)
Description of key information
In a GLP-study according to OECD test guideline 201 the registered substance did not show any algae toxicity at the loading level of 100 mg/L.
Key value for chemical safety assessment
- EC50 for freshwater algae:
- 100 mg/L
- EC10 or NOEC for freshwater algae:
- 100 mg/L
Additional information
For the registered substance, one algae toxicity study was available. As this study was conducted under GLP-conditions according to an OECD test guideline it was considered as Klimisch 1.
The toxicity of the regsistered substance to the unicellular freshwater green alga Desmodesmus subspicatus was determined according to the principles of OECD 201. The aim of the study was to assess the effects on growth rate and biomass production over a period of 72 h. The study was conducted under static conditions with an initial cell density of nominally 10E03 - 10E04 cells/mL. Based on the results of a range-finding test, the study was conducted as a limit test with the water accommodated fraction (WAF, 100 mg/L). Per definition of the WAF all terms related to concentration levels were given as loading levels because partly dissolved compounds and mixtures cannot be related to concentrations. Six replicates were tested for the test item WAF and control. Environmental conditions were determined to be within the acceptable limits. The loading of the test substance was analysed at test start and test end via GC-MS. All effect values are given based on the nominal loading levels of the test item. The registered substance did not show any (growth rate and biomass) algae toxicity at the loading level of 100 mg/L (BPCN, 2006)
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