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EC number: 946-188-6 | CAS number: -
The objective of the study was to assess the toxicity of test item CUCURBITURIL when administered as a single oral gavage dose to rats. The results of the study allow the test item to be ranked according to most classification systems currently used. Study performed in accordance with the study plan, OECD 423 (17th December 2001), Commission Regulation (EC) NO 440/2008 of 30 May 2008, B.1.Tris, EPA Health Effects Test Guidelines (OCSPP 8770.1100), United States, EPA 712-C-98-190 (1998) and the Principles of Good Laboratory Practice (Hungarian GLP Regulations: 42/2014. (VIII. 19.) EMMI decree of the Ministry of Human Capacities which corresponds to the OECD GLD, ENV/MC.CHEM (98)17).
Under the conditions of this study, the acute oral LD50 value of the test item CUCURBITURIL was found to be above 5000 mg/kg bw in female CRL: (WI) rats. According to the GHS criteria, CUCURBITURIL can be ranked as “Unclassified” for acute oral exposure.
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