2,20:3,19-Dimethano-2,3,4a,5a,6a,7a,8a,9a,10a,11a, 12a,13a,14a,15a,16a,17a,19 ,20,21a,22a,23a,24a,25a,26a,27a,28a,29a,30a,31a,32a,33a,34a-dotriacontaazabispentaleno [1''',6''':5'',6'',7''] cycloocta[1'',2'',3'':3'',4'']pentaleno[1'',6'':5',6',7']cycloocta[1',2',3':3',4']pentaleno[1',6':5,6,7]cycloocta[1,2,3-gh:1',2',3'-g'h']cycloocta[1,2,3-cd:5,6,7-c'd']dipentalene-1,4,6,8,10,12,14,16,18,21,23,25,27,29,31,33-hexadecone, hexadecahydro-, stereoisomer,2,18:3,17-Dimethano-2,3, ,4a,5a,6a,7a,8a,9a,10a,11a,12a,13a,14a,15a,17,18,19a, 20a,21a,22a,23a,24a, 25a,26a,27a,28a,29a,30a-octacosaazabispentaleno[1''',6''':5'',6'',7'']cycloocta [1'',2'',3'':3'',4''] pentaleno[1'',6'':5',6',7']cycloocta[1',2',3':3',4']pentaleno[1',6':5,6,7]cycloocta[1,2,3-cd:1',2',3'-gh]pentalene-1,4,6,8,10,12,14,16,19,21,23,25,27,29-tetradecone, tetradecahydro-, stereoisomer, 1H,4H,12H,15H-2,14:3,13-Dimethano-5H,6H,7H,8H,9H,10H,11H,16H,17H,18H,19H,20H,21H,22H-2,3,4a,5a,6a,7a,8a,9a,10a,11a,13,14,15a,16a,17a,18a,19a,20a,21a,22a-eicosaazabispentaleno [1'',6'':5',6',7']cycloocta[1',2',3':3',4']pentaleno[1',6':5,6,7]cycloocta[1,2,3-cd:1',2',3'-gh]pentalene-1,4,6,8,10,12,15,17,19,21-decone, decahydro-, stereoisomer

Density

Link to relevant study record(s)

Reference

Endpoint:

relative density

Type of information:

experimental study

Adequacy of study:

key study

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

EU Method A.3 (Relative Density)

Version / remarks:

2008

Deviations:

no

Qualifier:

according to guideline

Guideline:

OECD Guideline 109 (Density of Liquids and Solids)

Version / remarks:

2012

Deviations:

no

GLP compliance:

yes (incl. QA statement)

Type of method:

pycnometer method

Key result

Type:

relative density

Density:

1.536 other: no dimension

Temp.:

20 °C

Remarks on result:

other:

TABLE - DENSITY AND RELATIVE DENSITY OF TEST ITEM

 

DENSITY AND RELATIVE DENSITY OF TEST ITEM
Parameter	Replications
	R1	R2	R3
Mass of empty pyknometer (g)	23.4435	23.4279	17.8823
Mass of empty pyknometer +Lid (g)	29.0871	28.7141	23.2112
Mass of empty pyknometer +Lid + test item (g)	32.3158	31.6886	26.2586
Mass of empty pyknometer +Lid + test item wetting solution (g)	57.7653	56.6921	50.9746
Volume of wetting solution (mL)	25.4234	24.9778	24.6906
Mass of test item (g)	3.2287	2.9745	3.0474
Density of test item (g/cm^3)	1.5274	1.5437	1.5356
Mean density of test item (g/cm^3)	1.536
Mean density of test item (kg/m^3)	1536
Density of standard water at 4°C	1.000
Relative density of test item(D^204)	1.536

 

 

Conclusions:

The mean relative density of the reaction mass of cucurbit[6]uril, cucurbit[7]uril and cucurbit[8]uril was found to be 1.536 at 20 deg C using the pyknometer method.

Executive summary:

The purpose of this study was to determine the relative density of the reaction mass of cucurbit[6]uril, cucurbit[7]uril and cucurbit[8]uril. The study was performed in accordance with the OECD guideline 109 and Regulation (EC) 440/2008, Annex Part A test A3. The density, determined by the pyknometer method, of the solid test item at 20°C was 1536 kg/m³. The relative density (D²⁰₄) was 1.536.

Description of key information

A GLP study was conducted to determine density and relative density for the reaction mass of cucurbit [6]uril, cucurbit[7]uril and cucurbit[8]uril in accordance with current OECD and EU testing guidelines, using the pyknometer method. The density of the solid test item was 1536 kg/m³at 20°C. The relative density(D²⁰₄) was 1.536.

Key value for chemical safety assessment

Relative density at 20C:

1.536