Registration Dossier
Registration Dossier
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EC number: 202-124-2 | CAS number: 92-09-1
Ecotoxicological Summary
Administrative data
Hazard for aquatic organisms
Hazard for air
Hazard for terrestrial organisms
Hazard for predators
Additional information
Conclusion on classification
Classification relevant information
Degradation
- Not readily biodegradable: 11% and 20% after 28 d (OECD 301B); RA from CAS 25646-71-3
Bioaccumulation
- Log Kow = < -5.1 at 19.9 °C (OECD 107, estimation method); RA from CAS 25646-71-3
Aquatic acute toxicity
- Aquatic invertebrates: EC50 (48 h) = 3.2 mg/L (nominal, OECD 202, Daphnia magna); RA from CAS 25646-71-3
- Algae: EC50 (7 d) = 0.4 mg/L (yield, Selenastrum capricornutum, modification of the provisional algal assay procedure (PAAP)); RA from CAS 25646-71-3
Classification according to CLP
Based on the read across data N-[2-[(4-amino-m-tolyl)ethylamino]ethyl]methanesulphonamide is not rapidly degradable and has a low potential for bioaccumulation. Adequate long term toxicity data are not available and therefore the chronic classification is based on the short term data. Furthermore the source substance bears a harmonized classification, which was taken into account for N-[2-[(4-amino-m-tolyl)ethylamino]ethyl]methanesulphonamide. On this basis the substance is classified and labelled as Acute Cat. 1 (H400) and Chronic Cat. 1 (H410) for environmental hazard according to the consolidated version of Regulation (EC) No 1272/2008 and further amendments (ATPs).
M-factor for acute aquatic toxicity: 1
M-factor for chronic aquatic toxicity: 1 (According to the ECHA guidance on the application of the CLP criteria 2017, in cases where chronic data are not available, the resulting M-factor derived for acute aquatic hazard classification is also applied to the long-term aquatic hazard classification.)
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