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Administrative data

Endpoint:
vapour pressure
Type of information:
experimental study
Adequacy of study:
key study
Study period:
27 Nov 2018 to 06 Dec 2018
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2019
Report date:
2019

Materials and methods

Test guidelineopen allclose all
Qualifier:
according to guideline
Guideline:
OECD Guideline 104 (Vapour Pressure Curve)
Qualifier:
according to guideline
Guideline:
EU Method A.4 (Vapour Pressure)
Qualifier:
according to guideline
Guideline:
EPA OPPTS 830.7950 (Vapor Pressure)
GLP compliance:
yes
Type of method:
effusion method: isothermal thermogravimetry

Test material

Constituent 1
Chemical structure
Reference substance name:
N-[2-[(4-amino-m-tolyl)ethylamino]ethyl]methanesulphonamide
EC Number:
202-124-2
EC Name:
N-[2-[(4-amino-m-tolyl)ethylamino]ethyl]methanesulphonamide
Cas Number:
92-09-1
Molecular formula:
C12H21N3O2S
IUPAC Name:
N-{2-[(4-amino-3-methylphenyl)(ethyl)amino]ethyl}methanesulfonamide

Results and discussion

Vapour pressureopen allclose all
Test no.:
#1
Temp.:
20 °C
Vapour pressure:
<= 0 Pa
Test no.:
#1
Temp.:
20 °C
Vapour pressure:
<= 0 mm Hg
Test no.:
#2
Temp.:
25 °C
Vapour pressure:
<= 0 Pa
Test no.:
#2
Temp.:
25 °C
Vapour pressure:
<= 0 mm Hg

Any other information on results incl. tables

Vapour Pressure Results

Experiment 1

Temperature [°C]

log PT

PT [Pa]

PT [mm Hg]

20

-6.18

6.6 E-07

5.0 E-09

25

-5.83

1.5 E-06

1.1 E-08

 

Experiment 2

Temperature [°C]

log PT

PT [Pa]

PT [mm Hg]

20

-6.72

1.9 E-07

1.4 E-09

25

-5.35

4.7 E-07

3.3 E-09

 

Experiment 3

Temperature [°C]

log PT

PT [Pa]

PT [mm Hg]

20

-8.83

1.5 E-09

1.1 E-11

25

-8.36

4.4 E-09

3.3 E-11

 

The isothermal TGA effusion method was applied for the determination of the vapour pressure of N-[2-[(4-amino-m-tolyl)ethylamino]ethyl]methanesulphonamide.

The vapour pressure of the test item at 20 °C (293K) was: <=6.6 E-07 Pa, <=5.0 E-09 mmHg

The vapour pressure of the test item at 25 °C (298K) was: <=1.5 E-06 Pa, <=1.1 E-08 mmHg

The weight losses of the test item were obtained with a temperature program of above the melting temperature of the test item. According to this, the vapour pressure of the test item (which was, according to the method, extrapolated to 20 °C and 25 °C) could be slightly overestimated.

Applicant's summary and conclusion