Emblic, ext.

Toxicity to aquatic algae and cyanobacteria

Administrative data

Endpoint:

toxicity to aquatic algae and cyanobacteria

Remarks:

Sample sent to INTOX PVT. LTD. , 375, Urawade, Tal. Mulshi, Dist. Pune, Maharashtra, 412115, India.

Type of information:

experimental study

Adequacy of study:

key study

Reliability:

1 (reliable without restriction)

Data source

Reference

Reference Type:

study report

Title:

Unnamed

Year:

2018

Report date:

2018

Materials and methods

Test guideline

Qualifier:

according to guideline

Guideline:

OECD Guideline 201 (Freshwater Alga and Cyanobacteria, Growth Inhibition Test)

Deviations:

no

GLP compliance:

yes

Test material

Test material information

Constituent 1

Reference substance name:

Emblic, ext.

EC Number:

289-817-3

EC Name:

Emblic, ext.

Cas Number:

90028-28-7

IUPAC Name:

Beta-Glucogallin and Gallic acid are the main constituents of Emblica officinalis extract.

Test material form:

solid

Sampling and analysis

Analytical monitoring:

yes

Test organisms

Test organisms (species):

Raphidocelis subcapitata (previous names: Pseudokirchneriella subcapitata, Selenastrum capricornutum)

Study design

Test type:

static

Water media type:

freshwater

Limit test:

yes

Total exposure duration:

72 h

Test conditions

Test temperature:

24.7°C - 25.5°C

pH:

7.60 - 8.18

Reference substance (positive control):

not specified

Results and discussion

Effect concentrations

Key result

Duration:

72 h

Dose descriptor:

EC50

Effect conc.:

> 100 mg/L

Nominal / measured:

nominal

Conc. based on:

test mat.

Basis for effect:

growth rate

Applicant's summary and conclusion

Validity criteria fulfilled:

yes

Conclusions:

The Growth Inhibition value i.e. EC50 value for Emblica officinalis Extract in fresh water unicellular green algae Pseudokirchneriella subcapitata at 72hrs exposure period is estimated to be greater than 100 mg/L. The Study is performed as per OECD Guideline for testing of Chemicals Section 2, No. 201.