Registration Dossier

Data platform availability banner - registered substances factsheets

Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
melting point/freezing point
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2018
Report date:
2018

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
OECD Guideline 102 (Melting point / Melting Range)
GLP compliance:
no
Type of method:
method to determine freezing temperature

Test material

1
Reference substance name:
Silybum marianum extract
Molecular formula:
Not applicable
IUPAC Name:
Silybum marianum extract
Test material form:
liquid
Details on test material:
The test matérial contains 0.5% of tocophérol for stability

Results and discussion

Melting / freezing point
Key result
Melting / freezing pt.:
ca. 9.1 - ca. 9.6 °C
Decomposition:
no

Any other information on results incl. tables

The uncertainty of the measurement is estimated from the uncertainty of the thermometer ± 0.001 and is calculated to ± 0.3 ° C.

The freezing temperature of the sample of LIPOLAMI milk thistle ER is estimated at 282.5K with a repeatability of 0.02 %.

Applicant's summary and conclusion

Conclusions:
The freezing temperature of the sample of LIPOLAMI milk thistle ER is estimated at 282.5K with a repeatability of 0.02 %.
Executive summary:

The objective of this work is to determine the melting point / melting range of LIPOLAMI milk thistle ER. Since the sample is already in the liquid state, the objective is to determine the freezing or solidification point according to the OECD 102 guideline for testing of chemicals. The freezing temperature of the sample of LIPOLAMI milk thistle ER is estimated at 282.5K with a repeatability of 0.02 %.