Reaction mass of (4R)-4-(2-methoxypropan-2-yl)-1-methylcyclohexene and cis-1-methoxy-4-(2-methoxypropan-2-yl)-1-methylcyclohexane

Density

Link to relevant study record(s)

Reference

Endpoint:

relative density

Type of information:

experimental study

Adequacy of study:

key study

Study period:

12 Aug - 21 Sep 2016

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Remarks:

Study was conducted in accordance with international guidelines and in accordance with GLP. All guideline criteria were met.

Qualifier:

according to guideline

Guideline:

OECD Guideline 109 (Density of Liquids and Solids)

Deviations:

no

Qualifier:

according to guideline

Guideline:

EU Method A.3 (Relative Density)

Deviations:

no

Qualifier:

according to guideline

Guideline:

EPA OPPTS 830.7300 (Density / Relative Density / Bulk Density)

Deviations:

no

GLP compliance:

yes (incl. QA statement)

Type of method:

pycnometer method

Specific details on test material used for the study:

RADIOLABELLING INFORMATION (if applicable)
- Radiochemical purity: N/A
- Specific activity: N/A
- Locations of the label: N/A
- Expiration date of radiochemical substance: N/A

STABILITY AND STORAGE CONDITIONS OF TEST MATERIAL
- Storage condition of test material: Room temperature in the dark under nitrogen
- Stability under test conditions: Assumed stable
- Solubility and stability of the test substance in the solvent/vehicle: N/A
- Reactivity of the test substance with the solvent/vehicle of the cell culture medium: N/A

TREATMENT OF TEST MATERIAL PRIOR TO TESTING
- Treatment of test material prior to testing: N/A
- Preliminary purification step (if any): N/A
- Final dilution of a dissolved solid, stock liquid or gel: N/A
- Final preparation of a solid: N/A

FORM AS APPLIED IN THE TEST (if different from that of starting material)

OTHER SPECIFICS: N/A

Key result

Type:

relative density

Density:

905 kg/m³

Temp.:

20 °C

Table 1: Results of duplicate determinations of density

Measurement	Determination
	1	2
Mass of pycnometer (g)	17.4081	17.0613
Mass of pycnometer and purified water at 20.4 °C (g)	27.5638	27.2378
Mass of pycnometer and test item at 20.4 °C (g)	26.6126	26.2812
Temperature of test item (°C)	20.4
Density of water at 20.4 °C (kg/m3 )	998.12
Density (kg/m3 )	904.64	904.30
Relative density	0.9047	0.9043

Mean density = 904.5 kg/m3

Mean relative density = 0.905

Temperature = 20.0 ± 0.5˚C

Conclusions:

The relative density of the substance has been determined to be 0.905 at 20 ˚C.

Executive summary:

The relative density was determined using the pycnometer method in accordance with EU Method A.3, OECD 109 and EPA OPPTS 730:8300 guidance.

The relative density of the test substance has been determined to be 0.905 at 20 ˚C.

Description of key information

EU Method A.3, 2017 - The relative density was determined using the pycnometer method in accordance with EU Method A.3, OECD 109 and EPA OPPTS 730:8300 guidance.

The relative density of the test substance has been determined to be 0.905 at 20 ˚C.

Key value for chemical safety assessment

Relative density at 20C:

0.905