Registration Dossier

Administrative data

Endpoint:
vapour pressure
Type of information:
experimental study
Adequacy of study:
key study
Study period:
From 18 December 2018 to 05 April 2019
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2019
Report Date:
2019

Materials and methods

Test guidelineopen allclose all
Qualifier:
according to
Guideline:
EU Method A.4 (Vapour Pressure)
Version / remarks:
2016
Deviations:
no
Qualifier:
according to
Guideline:
OECD Guideline 104 (Vapour Pressure Curve)
Version / remarks:
2006
Deviations:
no
GLP compliance:
yes
Type of method:
effusion method: isothermal thermogravimetry

Test material

Reference
Name:
Unnamed
Type:
Constituent
Test material form:
liquid: viscous
Details on test material:
Batch (Lot) Number: R18 14728
Expiry date: 08 October 2020 (expiry date)
Physical Description: Dark amber viscous liquid
Purity/Composition: UVCB
Storage Conditions: At room temperature
Specific details on test material used for the study:
Decomposition temperature: 200°C

Results and discussion

Vapour pressureopen allclose all
Key result
Temp.:
20 °C
Vapour pressure:
0 Pa
Key result
Temp.:
25 °C
Vapour pressure:
0 Pa

Any other information on results incl. tables

Table: Results of the vapour pressure isothermal TGA analysis (substance)

Experiment

Temperature
[°C]

Weight loss
[µg/min]

νT
[g/cm2/h]

log νT

log PT

PT
[Pa]

1

140

1.66164

1.98E-4

-3.70

0.37

2.4

 

150

2.92565

3.49E-4

-3.46

0.68

4.8

 

160

5.05931

6.04E-4

-3.22

0.98

9.7

 

170

8.41704

1.00E-3

-3.00

1.26

18

2 (1)

140

0.544359

6.50E-5

-4.19

-0.24

0.57

 

150

1.67991

2.01E-4

-3.70

0.38

2.4

 

160

2.63039

3.14E-4

-3.50

0.62

4.2

 

170

5.12360

6.12E-4

-3.21

0.99

9.8

3

140

1.39105

1.66E-4

-3.78

0.27

1.9

 

150

2.50687

2.99E-4

-3.52

0.60

4.0

 

160

4.25815

5.08E-4

-3.29

0.89

7.8

 

170

7.17004

8.56E-4

-3.07

1.18

15

(1) not used for the result

Applicant's summary and conclusion

Conclusions:
The vapour pressure of the substance at 20°C and 25°C was determined to be 8.1E-6 Pa and 1.7E-5 Pa, respectively.
Executive summary:

The vapour pressure of the substance was determined using the isothermal thermogravimetric effusion method in a GLP study based on EC A.4 and OECD 104. Validation of the method was performed using a set of five reference substances. The vapour pressure regression curve (log PT as function of 1/T; with T in K) of the substance was constructed from weight losses measured at 140°C, 150°C, 160°C and 170°C.

The vapour pressure of the substance at 20°C and 25°C was extrapolated from the vapour pressure curve to be 8.1E-6 Pa and 1.7E-5 Pa, respectively.