Registration Dossier

Diss Factsheets

Administrative data

Endpoint:
boiling point
Type of information:
experimental study
Adequacy of study:
key study
Study period:
August - September 2017
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
comparable to guideline study with acceptable restrictions

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2018
Report date:
2018

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
other: Ph Eur method 2.2.11
Deviations:
yes
Remarks:
extrapolation to standard pressure was not performed.
Principles of method if other than guideline:
The procedure used was based on Ph Eur method 2.2.11 Determination of Distillation Range. 50.0 ml of sample were heated by means of a hemispherical heating mantle at ambient pressure (recorded as 100.1 kPa). Head temperature and amount of distillate were read and used to develop a distillation profile. Extrapolation to standard pressure of 101.3 kPa was not performed.
GLP compliance:
no
Type of method:
distillation method

Test material

Constituent 1
Reference substance name:
Cymbopogon nardus, ext.
EC Number:
289-753-6
EC Name:
Cymbopogon nardus, ext.
Cas Number:
89998-15-2
IUPAC Name:
Essential oil of Citronella obtained from the aerial parts of Cymbopogon nardus, (Poaceae), by steam distillation
Test material form:
liquid

Results and discussion

Boiling point
Key result
Boiling pt.:
>= 160 - <= 247 °C
Atm. press.:
1 atm
Remarks on result:
other:
Remarks:
Boiling range

Any other information on results incl. tables

 COMPOUND

 CAS  Boiling Point (ºC)
 camphene  79 -92 -5  160
 limonene  138 -86 -3  176
 citronellal  106 -23 -0  206
 citronellol  106 -22 -9  225
 geraniol  106 -24 -1  230
 geranyl acetate  105 -87 -3  240
 methyl iso eugenol  93 -16 -3

 262

Applicant's summary and conclusion

Conclusions:
Citronella oil (Cymbopogon Nardus) has a boiling range of 160-247ºC at ambient pressure.
Executive summary:

Citronella oil (Cymbopogon Nardus) has a boiling range of 160 - 247ºC at ambient pressure as determined using destillation method described in Ph Eur method 2.2.11