Registration Dossier
Registration Dossier
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EC number: 253-897-8 | CAS number: 38353-09-2
Biodegradation in water: screening tests
Administrative data
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- The final report study will be available 31/07/2018
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 018
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 301 B (Ready Biodegradability: CO2 Evolution Test)
- Version / remarks:
- The study was performed in compliance with the following regulations or guidelines:
• OECD Guidelines for Testing of Chemicals (1992) No. 301B "Ready Biodegradability; CO2 Evolution Test"
• Method C.4-C of Commission Regulation (EC) No. 440/2008
• US EPA Fate, Transport, and Transformation Test Guidelines OCSPP 835.3110 (Paragraph (m)) - Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
Test material
- Reference substance name:
- Pyrimidine-2-ol hydrochloride
- EC Number:
- 253-897-8
- EC Name:
- Pyrimidine-2-ol hydrochloride
- Cas Number:
- 38353-09-2
- Molecular formula:
- C4H4N2O.ClH
- IUPAC Name:
- pyrimidin-2-ol hydrochloride
- Test material form:
- solid: particulate/powder
Constituent 1
Study design
- Inoculum or test system:
- activated sludge (adaptation not specified)
- Details on inoculum:
- A mixed population of activated sewage sludge micro-organisms was obtained on 08 January 2018 from the aeration stage of the Severn Trent Water Plc sewage treatment plant at Loughborough, Leicestershire, UK, which treats predominantly domestic sewage.
Results and discussion
% Degradation
- Key result
- Parameter:
- % degradation (CO2 evolution)
- Value:
- ca. 31
- Sampling time:
- 28 d
Applicant's summary and conclusion
- Validity criteria fulfilled:
- yes
- Interpretation of results:
- not readily biodegradable
- Conclusions:
- The test item attained 31% biodegradation after 28 days and therefore cannot be considered to be readily biodegradable under the strict terms and conditions of OECD Guideline No. 301B.
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