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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Description of key information

An assessment on the acute oral toxicity of Trans-hex-2-en-1-ol was performed based on QSAR predictions supported by data on the substance and a suitable analogue. It was concluded that the substance is not acute toxic via the oral route.

Key value for chemical safety assessment

Acute toxicity: via oral route

Link to relevant study records
Reference
Endpoint:
acute toxicity: oral
Type of information:
other: Expert assessment
Adequacy of study:
key study
Study period:
2018
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: An assessment was performed based on QSAR predictions supported by data on the substance and a suitable analogue
Qualifier:
no guideline required
Principles of method if other than guideline:
An assessment was performed based on QSAR predictions supported by data on the substance and a suitable analogue
GLP compliance:
no
Test type:
other: An assessment was performed based on QSAR predictions supported by data on the substance and a suitable analogue
Limit test:
no
Key result
Sex:
male/female
Dose descriptor:
LD50
Effect level:
> 2 000 mg/kg bw
Based on:
test mat.
Remarks on result:
other: An assessment was performed based on QSAR predictions supported by data on the substance and a suitable analogue
Interpretation of results:
GHS criteria not met
Conclusions:
Trans-hex-2-en-1-ol substance is not acute toxic via the oral route and does not meet the criteria for classification according to Regulation (EC) No.1272/2008.
Executive summary:

An assessment on the acute oral toxicity of Trans-hex-2-en-1-ol was performed based on QSAR predictions supported by data on the substance and a suitable analogue. It was concluded that the substance is not acute toxic via the oral route and does not meet the criteria for classification according to Regulation (EC) No.1272/2008.

Endpoint conclusion
Endpoint conclusion:
no adverse effect observed
Dose descriptor:
LD50
Value:
2 000 mg/kg bw

Additional information

Justification for classification or non-classification

Trans-hex-2-en-1-ol does not meet the criteria for classification as acute toxic via the oral route in accordance to Regulation (EC) No.1272/2008.