Registration Dossier

Administrative data

Endpoint:
acute toxicity: oral
Type of information:
other: Expert assessment
Adequacy of study:
key study
Study period:
2018
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: An assessment was performed based on QSAR predictions supported by data on the substance and a suitable analogue

Data source

Reference
Reference Type:
other: expert assessment
Title:
Unnamed
Year:
2018
Report Date:
2018

Materials and methods

Test guideline
Qualifier:
no guideline required
Principles of method if other than guideline:
An assessment was performed based on QSAR predictions supported by data on the substance and a suitable analogue
GLP compliance:
no
Test type:
other: An assessment was performed based on QSAR predictions supported by data on the substance and a suitable analogue
Limit test:
no

Test material

Reference
Name:
Unnamed
Type:
Constituent

Results and discussion

Effect levels
Key result
Sex:
male/female
Dose descriptor:
LD50
Effect level:
> 2 000 mg/kg bw
Based on:
test mat.
Remarks on result:
other: An assessment was performed based on QSAR predictions supported by data on the substance and a suitable analogue

Applicant's summary and conclusion

Interpretation of results:
GHS criteria not met
Conclusions:
Trans-hex-2-en-1-ol substance is not acute toxic via the oral route and does not meet the criteria for classification according to Regulation (EC) No.1272/2008.
Executive summary:

An assessment on the acute oral toxicity of Trans-hex-2-en-1-ol was performed based on QSAR predictions supported by data on the substance and a suitable analogue. It was concluded that the substance is not acute toxic via the oral route and does not meet the criteria for classification according to Regulation (EC) No.1272/2008.