Registration Dossier

Diss Factsheets

Physical & Chemical properties

Vapour pressure

Currently viewing:

Administrative data

Link to relevant study record(s)

Reference
Endpoint:
vapour pressure
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2017-07-10 / 2018-03-26
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Reason / purpose for cross-reference:
reference to same study
Reason / purpose for cross-reference:
reference to same study
Reason / purpose for cross-reference:
reference to same study
Reason / purpose for cross-reference:
reference to same study
Reason / purpose for cross-reference:
reference to same study
Reason / purpose for cross-reference:
reference to same study
Reason / purpose for cross-reference:
reference to same study
Reason / purpose for cross-reference:
reference to same study
Qualifier:
according to guideline
Guideline:
OECD Guideline 104 (Vapour Pressure Curve)
Deviations:
no
Qualifier:
according to guideline
Guideline:
EU Method A.4 (Vapour Pressure)
Deviations:
no
GLP compliance:
yes (incl. QA statement)
Type of method:
effusion method: isothermal thermogravimetry
Test no.:
#1
Temp.:
20 °C
Vapour pressure:
0 hPa
Key result
Test no.:
#2
Temp.:
25 °C
Vapour pressure:
0 hPa
Transition / decomposition:
no

The results of the isothermal TGA analysis for the test item and the vapour pressure at 20°C and 25°C are given in the tables below. The vapour pressure regression curve of the log PT of the test item as function of the reciprocal temperatures was: log PT = -3340 × 1/T + 9.01 (r = 0.994, n = 8).

Results of the Vapour pressure Isothermal TGA Analysis

Temperature
[°C]

Weight loss
[µg/min]

νT
[g/cm2/h]

logνT

logPT

PT
[Pa]

100

0.871920

1.04 x 10-4

-3.98

0.04

1.1

 

0.864904

1.03 x 10-4

-3.99

0.03

1.1

110

1.44376

1.72 x 10-4

-3.76

0.32

2.1

 

1.49897

1.79 x 10-4

-3.75

0.34

2.2

120

2.08916

2.49 x 10-4

-3.60

0.52

3.3

 

2.17778

2.60 x 10-4

-3.59

0.55

3.5

130

2.85610

3.41 x 10-4

-3.47

0.70

5.0

 

2.93436

3.50 x 10-4

-3.46

0.71

5.2

Vapour Pressure of the Test Item

Temperature
[°C]

logPT

PT
[Pa]

PT
[mm Hg]

20

-2.38

4.2 x 10-3

3.1 x 10-5

25

-2.19

6.5 x 10-3

4.9 x 10-5

Conclusions:
The vapour pressure of the test item was 0.000042 hPa at 20°C (293K) and 0.000065 hPa at 25°C (298K).
Executive summary:

The isothermal TGA effusion method was applied for the determination of the vapour pressure of the test item according to OECD Guideline 104 and EU Method A.4. The vapour pressure of the test item was 0.000042 hPa at 20°C (293K) and 0.000065 hPa at 25°C (298K).

Description of key information

The isothermal TGA effusion method was applied for the determination of the vapour pressure of the test item according to OECD Guideline 104 and EU Method A.4. The vapour pressure of the test item was 0.000042 hPa at 20°C (293K) and 0.000065 hPa at 25°C (298K).

Key value for chemical safety assessment

Vapour pressure:
0 hPa
at the temperature of:
25 °C

Additional information

One reliable experimental study is available and is selected as key study (Charles River, 2018). It was performed according to OECD Guideline 104 and EU Method A.4, and under GLP conditions.

Categories Display