Registration Dossier

Administrative data

Endpoint:
vapour pressure
Type of information:
experimental study
Adequacy of study:
key study
Study period:
From 22/12/2017 to 20/09/2018
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2018
Report Date:
2018

Materials and methods

Test guidelineopen allclose all
Qualifier:
according to
Guideline:
OECD Guideline 104 (Vapour Pressure Curve)
Version / remarks:
23 March 2006
Deviations:
no
Qualifier:
according to
Guideline:
EU Method A.4 (Vapour Pressure)
Version / remarks:
23 July 2009
Deviations:
no
GLP compliance:
yes (incl. certificate)
Type of method:
effusion method: Knudsen cell

Test material

Reference
Name:
Unnamed
Type:
Constituent
Test material form:
liquid

Results and discussion

Vapour pressureopen allclose all
Key result
Test no.:
#1
Temp.:
20 °C
Vapour pressure:
0.015 Pa
Key result
Test no.:
#1
Temp.:
25 °C
Vapour pressure:
0.026 Pa
Key result
Test no.:
#2
Temp.:
20 °C
Vapour pressure:
0.013 Pa
Key result
Test no.:
#2
Temp.:
25 °C
Vapour pressure:
0.028 Pa

Any other information on results incl. tables

Triisononylamine: vapour pressure determination

 

First trial

 

Mass loss (mg)

Mass loss duration (s)

Vapourpressure (Pa)

Temperature (K)

1/T (K-1)

Log10(p)

1.318

600

11.1640

370.25

0.0027

1.0478

3.003

600

25.8827

383.35

0.0026

1.4130

7.194

600

63.1187

397.25

0.0025

1.8002

15.726

600

140.5406

412.15

0.0024

2.1478

 

A plot of Log10(p) versus reciprocal temperature (1/T) (with p in Pa and T in K) gives the following statistical data using an unweighted least square treatment.

Slope              -4029.6

Intercept         11.931              

                   0.9996

The results obtained indicate the following vapour pressure relationship:

Log10(p (Pa)) = -4029.6 / T (K) +11.931

The above equation yields avapourpressure of 1.53. 10-2 Pa at 293.15 K and 2.60. 10-2 Pa at 298.15 K.

 

Second trial

 

Mass loss (mg)

Mass loss duration (s)

Vapourpressure (Pa)

Temperature (K)

1/T (K-1)

Log10(p)

1.216

600

10.2986

370.15

0.0027

1.0128

2.981

600

25.7031

383.65

0.0026

1.4100

7.229

600

63.4737

397.85

0.0025

1.8026

15.803

600

141.3657

412.95

0.0024

2.1503

 

A plot of Log10(p) versus reciprocal temperature (1/T) (with p in Pa and T in K) gives the following statistical data using an unweighted least square treatment.

Slope              -4079

Intercept         12.039

                   0.9994

The results obtained indicate the following vapour pressure relationship:

Log10(p (Pa)) = -4079 / T(K) + 12.039

The above equation yields avapourpressure of 1.33. 10-2 Pa at 293.15 K and 2.28. 10-2 Pa at 298.15 K.

 

Summary of Results

 

Trial

Vapour pressure at 293.15 K

Vapour pressure at 298.15 K

1

1.53. 10-2Pa

2.60. 10-2Pa

2

1.33. 10-2Pa

2.28. 10-2Pa

Mean

1.43. 10-2Pa

2.44. 10-2Pa

 

The test item did not change in appearance under the conditions used in the determination.

Applicant's summary and conclusion

Conclusions:
The vapour pressure of Triisononylamine was measured using the Knudsen effusion method as described in EU method A.4 and OECD 104. Two trials were performed. For each trial, four pairs temperature/mass loss were used to calculate corresponding vapour pressure of the substance at specified temperatures. Then the logarithm of the vapour pressure log10 (p(Pa)) is plotted against 1/T(K), and the regression curve is used to calculate the vapour pressure of the substance at 20°C and 25°C.
From the linear regression obtained in the first trial, the vapour pressure of test item Triisononylamine was calculated as 1.53. 10-2 Pa at 20°C and 2.60. 10-2 Pa at 25°C.
From the linear regression obtained in the second trial, the vapour pressure of test item Triisononylamine was calculated as 1.33. 10-2 Pa at 20°C and 2.28. 10-2 Pa at 25°C.
The difference between the trials at 25°C is less than 20%.
Therefore, the results of this study are considered valid.
In conclusion, the vapour pressure of Triisononylamine is 1.43. 10-2 Pa at 20°C and 2.44. 10-2 Pa at 25°C.
Executive summary:

A study was performed to determine the vapour pressure of the test item Triisononylamine. The method followed was designed to be compliant with the OECD Guideline for Testing of Chemicals No. 104, "Vapour Pressure", adopted in March 2006 and Regulation (EC) No 761/2009, EC A4, 23 July 2009. Tests were conducted according GLP.

In this dynamic method, the mass of the test substance flowing out per unit of time of a Knudsen cell in the form of vapour, through a micro-orifice under ultra-vacuum conditions was determined at various specified temperatures (from 96.9°C to 139.8°C). The Hertz-Knudsen equation was used to calculate the vapour pressure corresponding to the mass loss rate.

The Log10 (Vapour Pressure (Pa)) was plotted against 1/T (K) and a linear function was obtained. With this equation, the vapour pressure has been calculated for temperatures of 20°C and 25°C.

Two trials were conducted and five points were recorded for each trial.

Log10 (Vapour Pressure (Pa)) was plotted against reciprocal temperature and values of vapour pressure were calculated at 20°C and 25°C with the linear function parameters (slope and intercept):

From the linear regression obtained in the first trial, the vapour pressure of test item Triisononylamine was calculated as 1.53. 10-2 Pa at 20°C and 2.60. 10-2 Pa at 25°C.

From the linear regression obtained in the second trial, the vapour pressure of test item Triisononylamine was calculated as 1.33. 10-2 Pa at 20°C and 2.28. 10-2 Pa at 25°C.

Calculated values respect validity criteria (less than 20% of difference) and the linear functions obtained own a correlation coefficient R² over 0.95. Moreover the calculated values showed good correspondence with the experimentally determined ones.

In conclusion, the vapour pressure of Triisononylamine is 1.43. 10-2 Pa at 20°C and 2.44. 10-2 Pa at 25°C.