Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 231-672-5 | CAS number: 7681-55-2
Acute Toxicity: oral
Administrative data
- Endpoint:
- acute toxicity: oral
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Study period:
- not specified
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- secondary literature
Data source
Reference
- Reference Type:
- publication
- Title:
- The effects of administration of sodium iodate to man and animals
- Author:
- Murray MM
- Year:
- 1 953
- Bibliographic source:
- World Hlth Org. (9) 211-216
Materials and methods
Test guideline
- Qualifier:
- no guideline available
- Principles of method if other than guideline:
- Acute toxicity tests were made on mice by Dr. W. L. M. Perry at the National Institute for Medical Research, London. This publication reports on the results from these tests.
- GLP compliance:
- not specified
Test material
- Reference substance name:
- Sodium iodate
- EC Number:
- 231-672-5
- EC Name:
- Sodium iodate
- Cas Number:
- 7681-55-2
- Molecular formula:
- HIO3.Na
- IUPAC Name:
- sodium iodate
Constituent 1
Test animals
- Species:
- mouse
- Strain:
- not specified
- Sex:
- not specified
Administration / exposure
- Route of administration:
- oral: unspecified
Results and discussion
Effect levelsopen allclose all
- Sex:
- not specified
- Dose descriptor:
- other: mortality (mice)
- Effect level:
- 250 mg/kg bw
- Based on:
- not specified
- Remarks on result:
- other: 0/10 mice died at this dose level
- Sex:
- not specified
- Dose descriptor:
- other: mortality (mice)
- Effect level:
- 750 mg/kg bw
- Based on:
- not specified
- Remarks on result:
- other: 7/10 mice died at this dose level
- Sex:
- not specified
- Dose descriptor:
- other: mortality (mice)
- Effect level:
- 2 500 mg/kg bw
- Based on:
- not specified
- Remarks on result:
- other: 10/10 mice died at this dose level
- Mortality:
- None of the animals dosed at 250 mg/kg bw died. At the dose level of 750 mg/kg bw 7 of the 10 animals died within 3 weeks. At 2500 mg/kg bw all of the animals died within 12 hours.
Applicant's summary and conclusion
- Conclusions:
- Following single oral administration of the test material to groups of 10 mice at dose levels of 250, 750 and 2500 mg/kg bw produced 0, 7 and 10 deaths, respectively.
- Executive summary:
The test material was dosed to groups of 10 mice at dose levels of 250, 750 and 2500 mg/kg bw.
No symptoms were reported in the group dosed at 250 mg/kg bw. At the dose level of 750 mg/kg bw 7 of the 10 animals died within 3 weeks. At 2500 mg/kg bw all of the animals died within 12 hours.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
