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Physical & Chemical properties

Partition coefficient

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Description of key information

log Pow – calculated on the basis of solubilities in n-octanol and water: 7.70 (OECD 107, EU A.8)  
log Pow - calculated from averaged log Koc value: 6.11 (calculation based on 2003 EU TGD)
log Pow - calculated using KOWWIN v1.68 (averaged value): 6.19 (EPIsuite v4.11)

Key value for chemical safety assessment

Log Kow (Log Pow):
6.67
at the temperature of:
20 °C

Additional information

The log Pow of 7.70 for the substance Hexadecan-1-ol, ethoxylated, < 2.5 EO (CAS 9004-95-9) was determined as the ratio of solubilities in n-octanol and water (computational method in OECD 107, EU A.8).

According to the approach developed for the Alcohol Ethoxylate Category, the value for chemical safety assessment logPow = 6.67 is derived in a weight-of-evidence approach on the basis of various log Pow values (average of 3 calculated values: 7.70, 6.11 and 6.19).

 

The following types of QSAR calculations were applied:

1. based on weight-averaged log Koc values using the TGD equation for predominantly hydrophobic substances: log Koc = 0.81 log Pow + 0.10 thus log Pow = (log Koc – 0.10)/0.81 (2003 EU Technical Guidance Document on Risk Assessment Part III, Chapter 4, Section 4.3, pp 24 – 27)

2. based on EPIsuite v 4.10, KOWWIN v 1.68 log Pow values for (possible) individual constituents of the substance.The averaged value was used as input value for derivation of the key value for chemical safety assessment.