Registration Dossier

Diss Factsheets

Administrative data

Endpoint:
surface tension
Type of information:
experimental study
Adequacy of study:
key study
Study period:
21 December 2001
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2002
Report date:
2002

Materials and methods

Test guidelineopen allclose all
Qualifier:
according to guideline
Guideline:
OECD Guideline 115 (Surface Tension of Aqueous Solutions)
Deviations:
no
Qualifier:
according to guideline
Guideline:
EU Method A.5 (Surface Tension)
Deviations:
no
GLP compliance:
yes (incl. QA statement)
Type of method:
ring method

Test material

Constituent 1
Chemical structure
Reference substance name:
-
EC Number:
439-750-2
EC Name:
-
Cas Number:
183487-56-1
Molecular formula:
Hill formula: C17H19BrClNO3 CAS formula: C17H19BrClNO3
IUPAC Name:
(4aR*,8aR*)-1-bromo-4a,5,9,10,11,12- hexahydro-3-methoxy-11-methyl-6H-ben zofuro[3a,3,2-ef][2]benzazepin-6-one hydrochloride
Test material form:
solid: particulate/powder
Specific details on test material used for the study:
- Batch n°: RT002113G3A231
- Analytical purity: 92.9%
- Expiration date: 08 April 2002
- Storage condition: at room temperature

Results and discussion

Surface tension
Key result
Surface tension:
68.5 mN/m
Temp.:
19.9 °C
Conc.:
0.1 vol%

Any other information on results incl. tables

Calibration:

Measured value of the surface tension of water: 70.825 mN/m

Surface tension of water at the test temperature: 72.899 mN/m

Calibration factor is: 72.899/70.825 = 1.0293

The calibration factor was determined by measuring the surface tension of water and comparing with the value available in the laboratory instrument files.

The corrected value was taken from a table compiled on the basis of the Harkins-Jordan correction.

Applicant's summary and conclusion

Conclusions:
The surface tension of T002113 in water (at a concentration of about 0.1%) was determined to be 68.5 mN/m at 19.9°C +/-0.4°C. Based on the criteria as outlined in the OECD Guideline, T002113 is not a surface active substance.